Lonza Sales Ag

Timothy J Soos

Christine Mccoy

Raymond J Moniz

Russell E Mcconnell

Ke Xu

Nikki Ross

EXTRACELLULAR VESICLES FOR VACCINE DELIVERY

The present disclosure relates to extracellular vesicles (EVs), e.g., exosomes, comprising a payload (e.g., an antigen, adjuvant, and/or immune modulator) and/or a targeting moiety. Also provided herein are methods for producing the EVs (e.g., exosomes) and methods for using the EVs (e.g., exosomes) to treat and/or prevent diseases or disorders, e.g., cancer, graft-versus-host disease (GvHD), autoimmune disease, infectious diseases, or fibrotic diseases.

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Boston, MA, United States of America

Timothy J Soos