The General Hospital Corporation

Timothy G Reese

Lawrence Leroy Wald

Hua Guo

Kawin Setsompop

Fuyixue Wang

Zijing Dong

Van J Wedeen

Systems and methods for accelerated diffusion-weighted magnetic resonance imaging using a tilted reconstruction kernel to synthesize unsampled k-space data in phase encoded and point spread function ('PSF') encoded k-space data are provided. Images reconstructed from the data have reduced B-related distortions and reduced T* blurring. In general, data are acquired with systematically optimized undersampling of the PSF and phase encoding subspace. Parallel imaging reconstruction is implemented with a Binhomogeneity informed approach to achieve greater than twenty-fold acceleration of the PSF encoding dimension. A tilted reconstruction kernel is used to exploit the correlations in the phase encoding-PSF encoding subspace. Self-navigated phase corrections are computed from the acquired data and used to synthesize the unsampled k-space data.

Accelerated diffusion-weighted magnetic resonance imaging with self-navigated, phase corrected tilted kernel reconstruction of phase encoded and point spread function encoded k-space

Systems and methods for accelerated magnetic resonance imaging using a tilted reconstruction kernel to synthesize unsampled k-space data in phase encoded and point spread function ('PSF') encoded k-space data are provided. Images reconstructed from the data have reduced B-related distortions and reduced T* blurring. In general, data are acquired with systematically optimized undersampling of the PSF and phase encoding subspace. Parallel imaging reconstruction is implemented with a Binhomogeneity informed approach to achieve greater than twenty-fold acceleration of the PSF encoding dimension. A tilted reconstruction kernel is used to exploit the correlations in the phase encoding-PSF encoding subspace.

Accelerated magnetic resonance imaging using a tilted reconstruction kernel in phase encoded and point spread function encoded K-space

A magnetic resonance imaging (MRI) method includes generating first and second spin populations within each of a plurality of pixels of a slice of an object. These spin populations have different phase histories. For each pixel, MRI signals from those spin populations are acquired at different times These MRI signals can then be used to determine a field strength difference between different pixels of the slice.

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Medford, MA, United States of America

Timothy G Reese