London Health Sciences Centre Research Inc.

Timothy Doherty

Arthur Brown

Greg A Dekaban

Ravi Menon

Jeff Holmes

Tony Rupar

Gregory A Dekaban

Ravi S Menon

Jeffrey Holmes

Lisa Fischer

Tanya Charyk Stewart

Charles A Rupar

J Kevin Shoemaker

Robert Bartha

Mark Daley

Douglas Dale Fraser

A method of diagnosing central nervous system injuries such as acquired brain injury (ABI) and/or acquired spinal cord injury (ASI), including mild TBI (concussion or blast wave), mild ASI (contusion, stretch or partial cord transection), non-TBI brain injury and/or non-TSI spinal cord injury in a subject (animal or human). The method includes (a) obtaining a biological test sample from the subject, identifying metabolites in the subject's sample using metabolomics thereby obtaining a subject's metabolite matrix and generating a subject's profile using the patient's metabolite matrix; and (b) using multivariate statistical analysis and machine learning to compare the subject's profile with predetermined set of profiles of CNS injuries and a predetermined set of profiles of controls to determine if the subject has a CNS injury.

Metabolomics profiling of central nervous system injury

Growing community of inventors

London, Canada

Timothy Doherty