The Texas A&m University System

Other

Engelhard Corporation

Texas Enterosorbents Inc.

Timothy D Phillips

Robert Hunt Carpenter

Dennis R Taylor

Keith A Delaney

Linda J Gordon

William C Gordon

Norman D Heidelbaugh

Beverly A Clement

A composition and method for use as a preventive therapy to mitigate the effects of environmental toxins, and particularly aflatoxins in a subject. The subject may be at risk for hepatocellular carcinoma and aflatoxicosis. The composition comprising: an effective amount of an isolated low sodium, calcium aluminosilicate clay in a powder form, wherein the isolated low sodium, calcium aluminosilicate clay contains acceptable levels of dioxins and priority toxic heavy metal contamination, and is capable of preferentially binding aflatoxins in the gastrointestinal tract.

Composition and methods for the enterosorption and management of toxins

It has been discovered that certain minerals, particularly various naturally occurring forms of aluminum oxide, will preferentially bind selective mycotoxins from a mixture of mycotoxins. These adsorbants, when used in various combinations and/or in conjunction with the adsorbants of the prior art, permit the construction of detector tubes which can resolve mycotoxins in solution and provide a semi-quantitative fluorescent determination of their concentration in feed or foodstuff samples. The detector tubes comprise transparent tubes packed with isolated layers of selected minerals. A solvent extract from a sample potentially contaminated with mycotoxins is passed through the column. As the mycotoxin mixture passes through the detector tube and is contacted by the various mineral adsorbants, selected mycotoxins are immobilized on a specific mineral while other mycotoxins and co-extracted organic compounds pass through that layer to be immobilized on subsequent downstream mineral layers. The presence of mycotoxins is determined by examining the developed detector tube under a long wave uv light source.

Selective immobilization and detection of mycotoxins in solution

A dry solid animal feed composition in which biodegradable feed is contaminated with a mycotoxin and is admixed with a mycotoxin inactivating agent comprising particles of a phyllosilicate mineral capable of inactivating mycotoxins, said particles being coated with a sequestering agent in an amount sufficient to enhance the mycotoxin inactivating capacity of said phyllosilicate.

Animal feed additive and method for inactivating mycotoxins present in

Growing community of inventors

College Station, TX, United States of America

Timothy D Phillips