Highland Instruments, Inc.

Timothy Andrew Wagner

Uri Tzvi Eden

William Edelman

Kyungmin Andy Lee

Paul James Mulhauser

Felipe Fregni

Laura Dipietro

An apparatus for interfacing between tissues being stimulated is provided. The apparatus includes an electric source capable of generating an applied electric field across a region of tissue and/or a means for altering at least one electromagnetic characteristic of the region of tissue relative to the applied electric field and an interface component, such interface component creating an interface between the region of tissue and the applied electric field or the means for altering at least one electromagnetic characteristic of the region of tissue.

Interface apparatus for stimulation of biological tissue

The invention generally relates to systems and methods for stimulating cellular function in biological tissue. In certain embodiments, the invention provides a method for stimulating cellular function within tissue that involves providing a first type of energy to a region of tissue, in which the first type is provided in an amount that inhibits cellular function within the region of tissue, and providing a second type of energy to the region of tissue, in which the second type is provided in an amount that facilitates cellular function within the region of tissue, wherein the combined effect stimulates cellular function within the tissue.

Systems and methods for stimulating cellular function in tissue

The invention generally relates to apparatuses and methods for stimulating and monitoring biological tissue. In certain aspects, the invention provides a system for stimulating and monitoring tissue, the system including a first energy source, a second energy source, and an imaging device, in which the system is configured such that the first and second energy sources target the same region of tissue and the combined effect of the first and second energy sources stimulates the region of tissue.

Systems and methods for stimulating and monitoring biological tissue

The invention generally relates to systems for measuring impedance change in order to detect a condition. In certain aspects, the invention provides systems for monitoring tissue and detecting a condition that include at least one energy source, a transduction unit, and a pattern recognition component that compares impedance signatures recorded from the transduction unit with a database of impedance signatures associated with medical conditions.

Systems for detecting a condition

The invention generally relates to methods for treating osteoarthritis. In certain embodiments, methods of the invention involve providing stimulation to a subject's central nervous system to modulate a signal sent to or from the subject's joint, thereby treating osteoarthritis.

Treatment methods

An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source.

Growing community of inventors

Somerville, MA, United States of America

Timothy Andrew Wagner