The General Hospital Corporation

Epivax, Inc.

Innatoss Laboratories B.v.

Aperisys, Inc.

Timothy Alan Brauns

Jeffrey A Gelfand

Mark C Poznansky

Michael R Hamblin

Liyi Huang

Daniela Vecchio

Giacomo Landi

Yingying Huang

Anne Searls De Groot

Anja Garritsen

Anja Scholzen

Leonard Jeffrey Moise

Ann Elizabeth Sluder

Stephen J McCormack

Huabiao Chen

The invention relates to fusion proteins comprising an antigen binding domain fused with a modified heat shock 70 protein. The invention further relates to methods of using the fusion proteins to induce an immune response to antigens and to treat diseases associated With antigens.

Antigen-binding fusion proteins with modified HSP70 domains

Compositions and methods for inducing a protective immune response against, to reduce a subject's risk of developing Q fever.

epitopes for T cell-targeted Q fever vaccines

A problem of incomplete inhibition of harmful cells/bacteria and short duration of time, after the photodynamic treatment, during which such cells may re-grow, is solved by exposing the target bacteria with a multi-component photosensitizer material formed by adding a predetermined potentiating chemical to a conventional single-component photosensitizer at the target, prior to irradiating the target with light. The multi-component photosensitizer is effectuated by forming a mix of the two chemical compositions or by sequential exposure of the bacteria to a single-component photosensitizer and the potentiating chemical of choice.

Antimicrobial photodynamic inactivation procedure and system

System and method for photo-dynamic procedure

Mass medical, e.g., cervical cancer, screening is provided to areas of the world where a lack of sufficient laboratory infrastructure and technical skills presently compromises the effectiveness of screening or even makes mass screening impossible. These methods are cost-effective and provide excellent sensitivity and specificity in cervical cancer screening.

Medical screening

Growing community of inventors

Roslindale, MA, United States of America

Timothy Alan Brauns