Gen-probe, Inc.

Oasis Biosciences Incorporated

Timothy A Riley

Bob Dale Brown

Lyle J Arnold

Aspects of the invention relate to novel oligonucleotides comprising universal and generic bases for use as primers and probes, as well as, methods of using said oligonucleotides for the diagnosis of disease.

Oligonucleotide probes and primers comprising universal bases for diagnostic purposes

Combinatorial libraries comprise first oligonucleotide analogs and second oligonucleotide analogs which are coupled together to form antisense molecules capable of binding target polynucleotides and activating an RNase, and ribozymes capable of cleaving polynucleotides.

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San Diego, CA, United States of America

Timothy A Riley