Leland Stanford Junior University

Tim R Blake

Robert M Waymouth

Paul A Wender

Ronald Levy

Ole Audun Werner Haabeth

Adrienne Sallets

Rebecca Mcclellan

Matthew Frank

Jessica R Vargas

Katherine Near

Nancy Benner

Colin Mckinlay

There are provided herein, inter alia, complexes, compositions and methods for the delivery of nucleic acid into a cell in vivo. The complexes, compositions and methods may facilitate complexation, protection, delivery and release of oligonucleotides and polyanionic cargos into target cells, tissues, and organs both in vitro and in vivo.

Hybrid immolative cell-penetrating complexes for nucleic acid delivery

There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues.

Immolative cell-penetrating complexes for nucleic acid delivery to the lung

Growing community of inventors

Palo Alto, CA, United States of America

Tim R Blake