Koninklijke Philips Corporation N.v.

Koninklike Philips N.v.

Koninklijke Philips Electronics N.v.

Philips Intellectual Property & Standards Gmbh

Tim Nielsen

Thomas Koehler

Peter Boernert

Andy Ziegler

Michael Grass

Bernhard Gleich

Sascha Krueger

Roland Proksa

Falk Uhlemann

Jan Jakob Meineke

Jan Hendrik Wuelbern

Ronny Ziegler

Christoph G Leussler

Johannes Adrianus Overweg

Peter Vernickel

Julien Senegas

Ulrich Wolfgang Katscher

Daniel Wirtz

Bernhard Johannes Brendel

Ingo Schmale

Jürgen Erwin Rahmer

Jurgen Weizenecker

Richard Moessel

Levinus Pieter Bakker

Jochen Peters

Jens Von Berg

Oliver Lips

Martinus Bernardus Van Der Mark

Irina Waechter-Stehle

Dominic J Heuscher

Frank Michael Weber

Eric Cohen-Solal

Peter Forthmann

Peter Koken

Christian Buerger

Nicole Schadewaldt

Karsten Sommer

Thomas Köhler

Rolf Jürgen Weese

Arne Ewald

Gabriele Marianne Beck

Christoph Günther Leussler

Sebastian Peter Michael Dries

Juergen Weizenecker

Stefanie Remmele

Robert Jochemsen

Torbjorn Vik

Peter Börnert

Michael Chun-chieh Lee

Michael Helle

Jürgen Weizenecker

Arjan Willem Simonetti

Gwenael Henri Herigault

Jan Hendrik Wulbern

Sebastian Hitziger

Juergen Rahmer

Mathijs Visser

Christophe Michael Jean Schülke

Thomas KÖHLER

A wireless passive marker device () to be tracked and a respective tracking system () are provided which make use of a sensing unit () comprising a resonator element () with piezoelectric properties and a coil element (), whereby an externally applied excitation field having a particular frequency is applied to act on the sensing unit () and wherein the sensing unit () responds to the externally applied excitation field by the resonator element () performing persisting mechanical oscillations in resonant mode, the persisting mechanical oscillations resulting in a piezoelectric voltage causing the coil element () to generate a magnetic field that may then be detected by the tracking system () and used for determining the position of the marker device () and/or sensing a physical property in the surrounding environment of the marker device ().

Passive wireless coil-based markers and tracking system

A system for receiving signals from a magneto-mechanical oscillator includes a main coil array adapted to receive a response signal of the magneto-mechanical oscillator and to transmit an excitation signal to the magneto-mechanical oscillator, and an additional coil for receiving a signal of the magneto-mechanical oscillator. A localizer is adapted to localize the additional coil and comprises a controller for controlling the main coil array and the additional coil such that a received localization signal is generated, a sensitivity provider for providing sensitivity information, and a processor for determining a position and/or orientation of the additional coil based on the provided sensitivity information and based on the received localization signal. A kit is provided for upgrading a system with a main coil array, by adding one or more additional coils and providing software for locating the one or more additional coils with the use of a pilot tone transmission.

System for receiving signals from a magneto-mechanical oscillator

The invention provides for a medical imaging system () comprising: a memory () for storing machine executable instructions () and a processor () for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive () magnetic resonance imaging data () descriptive of a subject (), wherein the magnetic resonance imaging data is segmented into sequential data portions (), wherein the magnetic resonance imaging data was acquired according to a three-dimensional magnetic resonance imaging protocol, wherein the magnetic resonance data within each of the sequential data portions is sampled in-plane using a rotating k-space sampling profile, wherein the magnetic resonance data within each of the sequential data portions is sampled using a segmented phase encoding in a thru-plane direction; and reconstruct () a navigator image () for each of the sequential data portions according to the three-dimensional magnetic resonance imaging protocol.

Self-navigation in three-dimensional magnetic resonance imaging

The invention provides for a medical instrument () comprising a magnetic resonance imaging system (). The medical instrument further comprises a subject support () with a support surface () configured for supporting at least a portion of the subject within an imaging zone (). The subject support comprises a radar array () embedded below the support surface. The medical instrument further comprises a radar system () for acquiring a radar signal () from the subject. The medical instrument further comprises a motion detection system () configured for acquiring a movement signal (). Execution of machine executable instructions () causes a processor () to: continuously () receive the radar signal; continuously () receive the movement signal; continuously () calculate a combined motion signal () from the radar system and the movement signal; and control () the magnetic resonance imaging system with the pulse sequence commands to acquire the magnetic resonance imaging data, wherein the acquisition of the magnetic resonance imaging data is controlled using the combined motion signal.

Motion tracking in magnetic resonance imaging using RADAR and a motion detection system

A method of setting an RF operating frequency of an MRI system () uses a first reference frequency signal, obtained from a geo-satellite positioning system, as a stable long term frequency reference. A second frequency source () is calibrated using the first frequency reference signal and the second frequency reference source () is then used as the master clock for the MRI system (), for setting the RF operating frequency.

Magnetic resonance imaging system and method using frequency calibration based on a signal from a geo-satellite positioning system

The invention provides for a medical imaging system () comprising a processor (). Machine executable instructions cause the processor to: receive () magnetic resonance data () comprising discrete data portions () that are rotated in k-space; bin () the discrete data portions into predetermined motion bins () using a motion signal value; reconstruct () a reference image () for each of the predetermined motion bins; construct () a motion transform () between the reference images; bin () a chosen group () of the discrete data portions into a chosen time bin (). Generate an enhanced image () for the chosen time bin using the chosen group fo the discrete data portions and the motion transform of each of the chosen group to correct the discrete data portions.

Motion compensated magnetic resonance imaging

Disclosed herein is a medical system (). The execution of machine executable instructions () causes a processor () to: receive () measured gradient echo k-space data (); receive () an off-resonance phase map (); reconstruct () an initial image () from the measured gradient echo k-space data; calculate () an upsampled phase map () from the off-resonance phase map; calculate () an upsampled image () from the initial image; calculating () a modulated image () by modulating the upsampled image with the upsampled phase map; calculate () a corrected image () comprising iteratively. The iterative calculation comprises: calculating () updated k-space data by applying a data consistency algorithm () to a k-space representation of the modulated image and the measured gradient echo k-space data and calculating () an updated image () from the updated k-space data. Calculation of the updated image comprises demodulation by the upsampled phase map and applying a smoothing algorithm.

Iterative reconstruction of gradient echo Magnetic Resonance Images

For delivering an image-guided radiation therapy treatment to a moving structure included in a region of a patient body a series of first images of the region of the patient body in different phases of a motion of the structure is acquired in accordance with a first imaging mode. The series of first images is associated with a series of second images of the patient body in essentially the same phases of the motion of the target structure, the second images being acquired in a second imaging mode. During the treatment, a third image is acquired using the second imaging mode during the radiation therapy treatment and a continuation of the radiation therapy treatment is planned on the basis of data relating to one of the first images selected on the basis of a comparison between the third image and the second images associated with the first images.

Image-guided radiation therapy

A system () and computer-implemented method are provided for data collection for distributed machine learning of a machine learnable model. A privacy policy data () is provided defining computer-readable criteria for limiting a selection of medical image data () to a subset of the medical image data to obfuscate an identity of the at least one patient. The medical image data is selected based on the computer-readable criteria to obtain privacy policy-compliant training data () for transmission to another entity. The system and method enable medical data collection at clinical sites without requiring manual oversight, and enables such selections to be made automatically, e.g., based on a request for medical image data which may be received from outside of the clinical site.

Medical data collection for machine learning

The invention provides for a magnetic resonance imaging system () comprising a memory () for storing machine executable instructions () and pulse sequence commands (). The pulse sequence commands are configured for acquiring a four dimensional magnetic resonance data set () from an imaging region of interest (). The four dimensional magnetic resonance data set is at least divided into three dimensional data magnetic resonance data sets () indexed by a repetitive motion phase of the subject. The three dimensional data magnetic resonance data sets are further at least divided into and indexed by k-space portions (). The magnetic resonance imaging system further comprises a processor () for controlling the magnetic resonance imaging system. Execution of the machine executable instructions causes the processor during a first operational portion () to iteratively: receive () a motion signal () descriptive of the repetitive motion phase; acquire () an initial k-space portion using the pulse sequence commands, wherein the initial k-space portion is selected from the k-space portions; store () the motion signal and the initial k-space portion in a buffer () for each iteration of the first operational portion; at least partially construct () a motion phase mapping () between the motion signal and the repetitive motion phase; and continue () the first operational portion until the motion phase mapping is complete. Execution of the machine executable instructions causes the processor to assign () the initial k-space portion for each iteration of the first operational portion in the temporary buffer to the four dimensional magnetic resonance data set using the motion phase mapping. Execution of the machine executable instructions causes the processor during a second operational portion () to iteratively: receive () the motion signal; determine () a predicted next motion phase using the motion signal and the motion phase mapping; select () a subsequent k-space portion () from the k-space portions of the four dimensional magnetic resonance data set using the predicted next motion phase; acquire () the subsequent k-space portion using the pulse sequence commands; rereceive () the motion signal; determine () a current motion phase using the re-received motion signal and the motion phase mapping; assign () the subsequent k-space portion to the four dimensional magnetic resonance data set using the current motion phase; and repeat () the second operational portion until the k-space portions for each repetitive motion phase has been assigned.

Acquisition of four dimensional magnetic resonance data during subject motion

The invention relates to a method of MR imaging of an object (). It is an object of the invention to enable MR imaging in the presence of motion of the imaged object, wherein full use is made of the acquired MR signal and a high-quality MR image essentially free from motion artefacts is obtained. The method of the invention comprises the steps of: generating MR signals by subjecting the object () to an imaging sequence comprising RF pulses and switched magnetic field gradients; acquiring the MR signals as signal data over a given period of time (T); subdividing the period of time into a number of successive time segments (SO, S, S, . . . Sn); deriving a geometric transformation (DVF, DVF, . . . DVFn) in image space for each pair of consecutive time segments (S, S, S, . . . Sn), which geometric transformation (DVF, DVF, . . . DVFn) reflects motion occurring between the two time segments of the respective pair; and reconstructing an MR image from the signal data, wherein a motion compensation is applied according to the derived geometric transformations (DVF, DVF, . . . DVFn). Moreover, the invention relates to an MR device () and to a computer program for an MR device ().

Magnetic resonance imaging using motion-compensated image reconstruction

The present invention is directed to a magnetic resonance imaging system with motion detection for examination of a patient (), the magnetic resonance imaging system comprising an RF coil arrangement with an RF coil () for transmitting and/or receiving an RF signal for generating a magnetic resonance image wherein the RF coil arrangement is provided with an additional RF sensor () for transmitting an RF transmit signal which is adapted for interacting with the tissue () of the patient () allowing to sense motion signals due to motions of the patient () simultaneously to transmitting and/or receiving the RF signal for generating the magnetic resonance image. In this way movements of a patient under examination in an MRI system may be detected in an efficient and reliable way.

Magnetic resonance imaging system with RF motion detection

MR imaging comprising the steps of: subjecting an object () to an imaging sequence of RF pulses and switched magnetic field gradients (GS, GP, GM), which imaging sequence is a steady state sequence comprising a plurality of repeatedly applied acquisition blocks (), wherein each acquisition block () comprises two units () in immediate succession, namely: i) a first unit () starting with an excitation RF pulse radiated toward the object (), with the duration of the first unit being an integer multiple of a given time interval T, and ii) a second unit () starting with a refocusing RF pulse radiated toward the object () and comprising a readout magnetic field gradient (GM) and a phase encoding magnetic field gradient (GP), with the duration of the second unit () being an integer multiple of the time interval T, acquiring one or more phase-encoded spin echo signals () in a sequence of acquisition blocks (), and reconstructing one or more MR images from the acquired spin echo signals (). Moreover, the invention relates to a MR device () and to a computer program for a MR device ().

Spin echo MR imaging

An iterative reconstruction is performed of multiple gradient echo MR imaging data to generate a reconstructed MR image (). The iterative reconstruction uses a model () that links the MR imaging data and the reconstructed MR image. The model includes a parameterized magnetic field fluctuation component (). During the performing of the iterative reconstruction, parameters of the parameterized magnetic field fluctuation component of the model are updated to optimize a cost function () dependent on partial derivatives of the reconstructed MR image with respect to the parameters of the parameterized magnetic field fluctuation component of the model. The image may be further processed to generate an R2* map (), an SWI image (), or a QSM map ().

Retrospective correction of field fluctuations in multiple gradient echo MRI

The invention provides for an MRI system () with an RF system for acquiring magnetic resonance data (). The RF system comprises a set of antenna elements (). The MRI system () further comprises a processor for controlling the MRI system (). Magnetic resonance data is acquired. Combined image data () is reconstructed. The reconstruction comprises transforming the acquired magnetic resonance data () from k-space to image space and combining the resulting image data. For each antenna element () magnetic resonance data () is simulated using the reconstructed combined image data (). The simulation comprises transforming the reconstructed combined image data () from image space to k-space. A phase correction factor is determined, The determination comprises calculating phase differences between the acquired magnetic resonance data () and the simulated magnetic resonance data (). The acquired magnetic resonance data () is corrected using the phase correction factor. In this way, the invention allows for correcting phase errors caused e.g. by subject motion such as respiration by B0 off-resonances, etc.

Data driven correction of phase depending artefacts in a magnetic resonance imaging system

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Hamburg, Germany

Tim Nielsen