Duke University

University of Pittsburgh

Other

The University of Alabama

Aeolus Pharmaceuticals, Inc.

Tim D Oury

James D Crapo

Brian J Day

Irwin Fridovich

Bruce A Freeman

Rodney J Folz

Michael Peter Trova

Ines Batinic-Haberle

Thomas W Gilbert

Michelle Manni

Naftali Kaminski

Jan J Enghild

Jan Johannes Enghild

Laura Voeghtly

Philip J Walther

Zuzana Valnickova

Ida B Thogersen

Provided herein are methods of preventing, lessening or treating pulmonary fibrosis in a subject. The methods comprise delivering an amount of a powdered extracellular matrix (ECM)-derived material to the respiratory system of the subject effective to prevent, lessen or treat pulmonary fibrosis in a subject. Also provided is an apparatus for delivering the powdered ECM-derived material to a subject.

Biologic scaffold for prevention of pulmonary fibrosis

A method is provided along with related reagent kits for aiding the diagnosis of IPF or other interstitial lung diseases, as well as for potential monitoring of disease progression or therapeutic response to treatment.

MMP activation peptide detection in biological samples

The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

Oxidant scavengers

Dectection of secreted Prostate Specific Antigen (PSA) by detecting the presence of an N-terminal activation peptide of PSA in a biological sample is described. The method may be used in screening for or diagnosing disease states associated with increased levels of secreted prostate specific antigen.

Method of detecting prostate specific antigen

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Wexford, PA, United States of America

Tim D Oury