Ablative Solutions, Inc.

Other

Angel Medical Systems Inc.

Vantis Vascular, Inc.

Cathco, Inc.

Cordis Corporation

Isostent, Inc.

Fischell Innovations, LLC

Medinnovations, Inc.

Medical Innovative Technologies R & D Limited Partnership

Adlore, Inc.

Crossliner, Inc.

Arrow International Investment Corp.

Tru Vue, Inc.

Magnolia Medical, LLC

Tim A Fischell

David R Fischell

Robert E Fischell

Andy Edward Denison

Darrin James Kent

Eric Thomas Johnson

Robert Ryan Ragland

Jeff Alan Burke

Christopher Scott Hayden

Frank S Saltiel

Jonathan Harwood

Vartan E Ghazarossian

Steven Almany

Steven R Johnson

Michael Sasha John

Jeffrey D Payne

Scott J S Fischell

Xiaoke Liu

Bruce Hopenfeld

Dieter Stockel

Daryl Lawson

Sean Salmon

Nicole Haratani

Christopher B Arena

Mark Zyzelewski

Richard L Harding

Timothy J Lynch

Robert F Fischell

James J Thompson

Todd H Turnland

Khaldoon Alaswad

Arunpreet Kahlon

Scott Js Fischell

A therapeutic apparatus for treating damaged tissue on a limb or body of a subject includes a wearable adapted to cover and be secured to the limb or body of a subject over damaged tissue. The wearable being configured to reduce pressure on the damaged tissue and adapted to deliver one or more treatments selected from the group consisting of heat, oxygen, electrical current, and light to the damaged tissue.

Apparatuses, systems, and methods for the treatment of damaged tissue

A rapid exchange guide wire system for rapid delivery of a guide wire to a blood vessel. The system has a main guide wire and rapid a rapid exchange tube attached to the main guide wire near a distal end of the main guide wire. The rapid exchange tube has a lumen which extends in a longitudinal direction and is configured to permit the rapid exchange tube to be reversibly displaceable in the longitudinal direction over a medical device having a cylindrical portion The medical device may be a guide wire, balloon angioplasty catheter, stent delivery catheter, atherectomy catheter, intravascular ultrasound catheter, blood flow measurement wire, optical coherence tomography catheter, or a stent-on-wire catheter.

Rapid exchange (monorail) guide wire system for rapid delivery of guide wire to a blood vessel

Methods, apparatuses, and systems for performing a valve replacement or repair. Apparatuses may include systems and may include an outer catheter, one or more interchangeable inner catheters, a guidewire and an expandable chordae tendinae deflector. Also described herein are rapid pacing sheaths that may be used with any of these apparatuses and methods.

Method and apparatus for antegrade transcatheter valve repair or implantation

A method and system for performing transseptal extracorporeal membrane oxygenation is disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. A first portion of the catheter system can remove blood from the patient, in some examples near the inferior vena cava. A second portion can return oxygenated blood to the patient, through the transseptal puncture and into the aorta.

Method and apparatus for catheter-based extracorporeal membrane oxygenation (ECMO)

An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes near the distal ends of the needles allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media.

Apparatus for effective ablation and nerve sensing associated with denervation

An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. The addition of an injection lumen at the proximal end of the catheter and openings in the needles adds the functionality of ablative fluid injection into the perivascular space for an integrated nerve sending and ablation capability.

Intravascular catheter with peri-vascular nerve activity sensors

Intravascular delivery system is designed for a safe and efficient access to secondary and tertiary vascular structures, such as the branches of the coronary sinus, to enhance the delivery and deployment of various catheters, such as, for example, pacemaker electrical leads. The over-the-wire system features a straight, or alternatively shaped, micro-catheter distal tip of an inner catheter that seamlessly cooperates with a peel-away reinforced outer catheter. The inner catheter and the peel-away reinforced outer catheter are advanced in their engaged mode of operation towards (or beyond) the target site. Subsequently, the inner and outer catheters are disengaged, and the inner catheter is removed from the outer catheter. A pacemaker lead may be advanced over the wire inside the outer catheter to the target site for deployment. Subsequently, the outer catheter is easily split and may be rapidly removed from the blood vessel.

Enhanced guide extension system for the efficient delivery of leads

An intravascular catheter for peri-vascular or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

Method for painless renal denervation using a peri-vascular tissue ablation catheter with support structures

The subject guide catheter extension system with a micro-catheter delivery catheter includes an outer sheath, an inner member extending within the sheath, and a mechanism for engagement/disengagement of the inner member to/from the sheath. Several mechanisms of engagement/disengagement between the inner and outer members are provided including a friction mechanism, threaded mechanism, pull away sheath, and engagement/disengagement mechanism for pusher's handles. The sheath and the inner member are modified for different engagement/disengagement mechanisms operation. A micro-catheter delivery system provides for an improved atraumatic crossability to the treatment site in an expedited and simplified fashion. During a procedure, a guidewire along with a guide catheter are advanced to the vicinity of the treatment site within a blood vessel. Subsequent thereto, the subject guide catheter extension system is manipulated to advance the micro-catheter along the guidewire inside the guide catheter towards and beyond the site of interest. Once the micro-catheter is in place, the outer sheath slides along the micro-catheter until reaching the lesion, and then the inner member is removed from the sheath, and the sheath then is ready for passing the treatment catheter (stent/balloon) towards the lesion to be treated.

Guide catheter extension system with a delivery micro-catheter configured to facilitate percutaneous coronary intervention

The subject guide catheter extension/pre-dilatation system includes an outer delivery sheath, an inner member extending within the sheath, and a mechanism for engagement/disengagement of the inner member to/from the sheath. The inner member is configured with a tapered distal tip having a delivery micro-catheter and a pre-dilatation balloon member attached to the tapered distal tip in proximity to the micro-catheter. The outer delivery sheath and the inner member are modified for different engagement/disengagement mechanisms operation. The delivery micro-catheter provides for an improved crossability for the balloon member to the treatment site in an atraumatic, expedited and convenient fashion. During the cardiac procedure, a guidewire and a guide catheter are advanced to the vicinity of the treatment site within a blood vessel. Subsequent thereto, the inner member and outer delivery sheath, in their engaged configuration, are advanced along the guidewire inside the guide catheter towards the site of treatment. Once at the treatment site, the balloon member is inflated for pre-dilatation treatment. Subsequently, the inner member is disengaged and retracted from the outer delivery sheath, and a stent is delivered to the treatment site inside the outer delivery sheath.

Intravascular delivery system and method for percutaneous coronary intervention

An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

Peri-vascular tissue ablation catheter with support structures

An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple penetrators advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, nerve sensing, nerve stimulation, or ablation by application of energy. The catheter can include a proximal handle for the advancement of guide tubes and penetrators.

Peri-vascular tissue access catheter with locking handle

An imaging catheter apparatus can include an elongate shaft assembly having a proximal shaft portion and a distal shaft portion. The shaft assembly can be configured to carry an imaging transducer such that the imaging transducer is locatable at or near a distal portion of the elongate shaft assembly. At least one coupler can be attached to the elongate shaft assembly. The at least one coupler configured to permit an end user to at least one of couple or attach at least one of a guidewire or an interventional medical device to the elongate shaft assembly via the at least one coupler. For example, the at least one coupler can include an elastic sleeve. The elastic sleeve can expand to accommodate passage of a guidewire or interventional medical device therethrough. Then, the elastic sleeve can relax or shrink to grip the interventional medical device, such as to secure or stabilize its position with respect to the imaging catheter, such as for performing a medical procedure.

User-attachable/detachable imaging catheter

Growing community of inventors

Kalamazoo, MI, United States of America

Tim A Fischell