Industrial Technology Research Institute

Academia Sinica

Tien-Soung Tong

Lain-Tze Lee

Yi-Cheng Cheng

Ying-Chu Shih

Hui-Ping Tsai

Po-Ting Chen

Yi-Ching Lee

Hung-Chi Chien

Cheng-Yu Lee

Jir-Mehng Lo

Kuo-Kuei Huang

Ting-Shou Chen

Shu-Jiau Chiou

Chang-Jen Huang

Rita P-y Chen

Yung-Feng Liao

Ying-Fei Tsai

Cheng-Li Fang

Jui-Hung Yen

Bo-Kai Wu

I-Horng Pan

Zong-Keng Kuo

Hsin-Chieh Wu

Hsin-Jan Yao

I-Huang Lu

Jenn-Line Sheu

Jennline Sheu

Hsiang-Wen Tseng

Mei-Wei Lin

Hui-Ju Liang

Ching-Huai Ko

Shyh-Horng Lin

Nai-Yun Hu

Bie-Shung Tsai

Chun-Chung Wang

Rita P-Y Chen

Disclosed herein is the novel use of use of aspp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus thespp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.

extract and uses thereof

The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract ofor an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract ofor an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.

Pharmaceutical compositions and method for inhibiting angiogenesis

An extract ofsp. in use of arthritis treatment is provided. The extract ofsp. and an active ingredient contained therein, antofine, are applicable to a method, pharmaceutical composition and dietary supplement for treatment of arthritis. A mass production of antofine from plant extracts is also provided.

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A method for treating or relieving inflammatory bowel disease (IBD) is provided, including administering an extract ofas an active ingredient to a subject. Themay be selected from the group consisting ofand a combination thereof.

Method for treating or relieving inflammatory bowel disease

A pharmaceutical composition with an immunomodulating function is provided, including an extract ofobtained by grinding the, adding the groundto a solvent and isolating the extract from the solvent, wherein thecomprisesand Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1&#x2dc;6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1&#x2dc;6, or combinations thereof.

Pharmaceutical composition with immunomodulating function

Growing community of inventors

Hsinchu, Taiwan

Tien-Soung Tong