Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

H4sep Kft

Magyar Tudományos Akadémia Természettudományi Kutatóközpont

Tibor Soós

Zoltán Dalicsek

Géza Timári

Zoltán Finta

Gábor Vlád

Ferenc Fülöp

István Szatmári

Gergely Szakács

Veronika Pape

Roberta Ferenczi-Palkó

György Dormán

András Füredi

Szilárd Tóth

Dóra Türk

The present invention is related to 8-hydroxy-quinoline derivatives having multidrug-resistance reversing activity with improved selectivity and increased cytotoxicity towards multidrug-resistant cancer cells, preparation thereof and use of the same in the treatment of cancer, especially multidrug-resistant variants thereof. 

MDR-reversing 8-hydroxy-quinoline derivatives

The invention relates to palladium(0) tris{tri-[3,5-bis(trifluoromethyl)-phenyl]-phosphine} complex of formula (I), as well as to its preparation and use.  This compound is outstandingly stable, and can be used as catalyst with excellent results.

Palladium catalyst, method for its preparation and its use

The invention relates to palladium(0)-tris{tri-[3,5-bis(trifluoromethyl)-phenyl]-phosphine} complex of formula (I), as well as to its preparation and use.  This compound is outstandingly stable, and can be used as catalyst with excellent results.

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Budapest, Hungary

Tibor Soós