Olympus Corporation

Tianyu Xie

Atsushi Okawa

Yasushige Ishihara

Toshiaki Watanabe

Akihiro Horii

Tadashi Hirata

Kazunari Tokuda

Hiroshi Tosaka

Hironobu Takizawa

Akio Uchiyama

Mamoru Kaneko

Naoki Miura

Toshiro Okamura

Yasuhiro Kamihara

Mitsuhiro Hara

A lesion extracting device includes a light source for emitting an excitation light toward a subject body, a control unit for changing an amount of the excitation light, a light irradiating and receiving portion for irradiating the excitation light to the subject body and receiving fluorescence generated from the subject body, a distance holding member for holding a distance between the subject body and the light irradiating and receiving portion at a predetermined value, a measuring unit for measuring the intensity of the fluorescence received by the light irradiating and receiving portion, and an extracting unit for extracting a lesion part of the subject body based on relationships between measured values of changes in the fluorescence intensity with respect to changes in the amount of the excitation light and information regarding the changes in the amount of the excitation light, the information being obtained from the control unit.

Lesion extracting device and lesion extracting method

A lesion extracting device having a control unit for changing an amount of the excitation light emitted toward a subject body, a measuring unit for measuring a change in the intensity of fluorescence generated from the subject body with respect to a change in the amount of the excitation light, and an extracting unit for calculating a ratio of the change in the intensity of fluorescence on the basis of a ratio of the change in the amount of the excitation light to the change in the intensity of fluorescence and for extracting a lesion part of the subject body on the basis of the ratio of the changes in the amount of the excitation light to the ratio of the changes in the intensity of fluorescence.

The invention includes an insertion portion, one end of which is inserted inside a lumen of a subject; an image-acquisition unit for acquiring an image of an interior wall in the lumen as a substantially circular or substantially ring-shaped interior wall image; a transformation processing unit for transforming, in the interior wall image, at least substantially ring-shaped images concerning the interior wall, whose distance from the one end is uniform, to substantially straight-line-shaped or substantially band-shaped images; a distance-measuring unit for measuring a distance moved by the insertion portion relative to the subject; and an image synthesizing unit for joining the transformed images on the basis of the distance moved measured by the distance-measuring unit.

Endoscope apparatus

An in-vivo information measurement apparatus having an insertion part; a light projection unit, provided at a tip of the insertion part, irradiates an examination site with intensity-modulated light which is intensity modulated at a first frequency; a light receiving unit receives return light from the examination site; an optical detector detects return light; an in-vivo information calculation unit calculates in-vivo information for the examination site based on a phase shift between a modulated detection signal, a detection signal from the optical detector is modulated at a second frequency, and a reference signal having a difference frequency equal to the difference between the first frequency and the second frequency; and a position moving mechanism moves at least one of a position at which the intensity-modulated light is emitted by the light projection unit and the position at which the return light is incident on the light receiving unit.

In-vivo information measurement apparatus

A fluorescent agent accumulation concentration measuring apparatus is configured to include a single-wavelength LED to radiate excitation light to a test bottle loaded in the inside, a barrier filter to transmit only fluorescence from the test bottle, a photoreceptor to receive the fluorescence through the barrier filter and output an electric signal, a detection processing circuit to conduct signal processing of the electric signal from the photoreceptor and detect the fluorescence intensity, and an operation circuitto compare the detection result from the detection processing circuit with an analytical pattern stored in a pattern storage portion and calculate the peak time of the accumulation concentration in a tissue of a sample in the test bottle.

Fluorescent agent concentration measuring apparatus, dose control apparatus, administration system, fluorescent agent concentration measuring method, and dose control method

A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.

Optical image pickup apparatus for imaging living body tissue

An optical probe system comprises an optical probe that is inserted into a body cavity, a light source that generates light which is irradiated to an object, and a high-magnification observation unit included in the distal section of the optical probe. The optical probe system further comprises: an image digitization unit that digitizes a luminance signal produced by the high-magnification observation unit; an image parameter sampling unit that samples an image parameter from an image; an optimization parameter calculation unit that calculates an optimization parameter on the basis of the image parameter; an image optimization unit that optimizes an image according to the optimization parameter; an image display device on which an optimized image is displayed; and a digital image preservation unit in which a digitized image is preserved.

Optical probe system

An attachmentthat is proximal to an optical probeincludes probe information holding meansthat holds probe information such as a scanning technique and an optical path length or the like. When the optical probeis connected (attached) to an observing device, probe information detecting means included in the observing deviceautomatically detects the probe information held in the optical probe. Based on the detected probe information, a scanning technique and an optical path length of reference light are set to values suitable to an actually connected optical probe

Optical imaging system and optical imaging detection method

An optical imaging apparatus includes an optical probe and an apparatus main body which controls and drives the optical probe via a connecting cable. The optical probe includes a low-coherence light source, a half mirror, an XY reflecting mirror scan, an objective optical system, a reflecting mirror, a modulating mirror, and a photo detector. In the optical probe, the modulating mirror and the objective optical system, as optical path length interlockingly adjusting elements, are integrally arranged to an optical path length interlockingly adjusting base, together with a reflecting-side lens. The optical probe has an advancing and regressing driving unit which advances and regresses the optical path length interlockingly adjusting base in the optical axis direction (Z direction).

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Akiruno, Japan

Tianyu Xie