University System of Maryland

United States of America, As Represented by the Secretary of Agriculture

Tianhong Chen

Gregory F Payne

William E Bentley

Gary W Rubloff

Reza Ghodssi

Hyunmin Yi

Maryann M Taylor

Li-Qun Wu

Eleanor M Brown

Rohan Fernandes

David A Small

Heather D Embree

A method is provided for electrochemically depositing a polysaccharide mass having a selected physical state. According to an embodiment, an electrically conductive support of a substrate is contacted with an aqueous solution including a selectively insolubilizable polysaccharide, and the selectively insolubilizable polysaccharide is electrochemically deposited on the electrically conductive support while controlling deposition conditions to form the polysaccharide mass having the selected physical state, such as that of a hydrogel. Deposition may be performed in a spatially and/or temporally controlled manner. 

Controlled electrochemical deposition of polysaccharide films and hydrogels, and materials formed therefrom

Gels and polymers comprising a polypeptide bound to a polysaccharide are disclosed. Specific polypeptides include, but are not limited to, polypeptides that comprise glutamine or tyrosine residues. Specific polysaccharides include, but are not limited to, chitosan. Gels and polymers of the invention can be used for the in vitro and in situ formation of protein-polysaccharide conjugates. Methods of making polypeptide/polysaccharide gels and polymers are also disclosed.

Polysaccharide-based polymers and methods of making the same

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Newark, DE, United States of America

Tianhong Chen