University of California

Northwestern University

Tian Xia

Andre E Nel

Mark C Hersam

Nikhita Mansukhani

Linda M Guiney

Ruibin Li

Jeffrey I Zink

Huan Meng

Zongxi Li

Monty Liong

Min Xue

Zhaoxia Ji

Derrick Y Tarn

Sanaz Gardner

In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (·C) density.

Identification and optimization of carbon radicals on hydrated graphene oxide for ubiquitous antibacterial coatings

In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (.C) density.

A submicron structure having a silica body defining a plurality of pores is described. The submicron body may be spherical or non-spherical, and may include a cationic polymer or co-polymer on the surface of said silica body. The submicron structure may further include an oligonucleotide and be used to deliver the oligonucleotide to a cell. The submicron structure may further include a therapeutic agent and be used to deliver the therapeutic agent to a cell. An oligonucleotide and therapeutic agent may be used together. For example, when the oligonucleotide is an siRNA, the composition may be used to decrease cellular resistance to the therapeutic agent by decreasing translation of a resistance gene.

Cationic polymer coated mesoporous silica nanoparticles and uses thereof

Growing community of inventors

Los Angeles, CA, United States of America

Tian Xia