University of Central Florida Research Foundation, Inc.

Southern Methodist University

Jamrm, LLC

Thu Q Nguyen

John D Buynak

Kyle Rohde

Noora M S A Al-Kharji

Maha Alqurafi

Rashmi Gupta

Weirui Chai

John Koch

Alisar Salah Zahr

Nirmal Shah

Tatiana Kelly

Provided are formulations that interact with the skin microbiome of a human patient such that when applied topically in therapeutically effective amounts at prescribed intervals, the formulations cause an increase in skin firmness, density, smoothness, elasticity and thickness resulting in a skin appearance that reflects overall skin health. In exemplary embodiments formulations include, without limitation, the following active components acting in concert with each other: a prebiotic component, a peptide component, a matrix metalloproteinases (MMPs) inhibitor component; and an antioxidant component; all present in a carrier base. The exemplary embodiments may be in the form of a cream, a lotion, a serum, or a hydrogel that facilitates delivery of these active components into the skin.

Formulations for enhancing skin firmness, density and thickness

The present invention includes a composition, method of making and method of using a novel C5-substituted carbapenem antibiotic of formula 1: 

C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment of mycobacterium tuberculosis and non-tubercular mycobacteria

C5-substituted carbapenem antibiotics, compositions containing such compounds, and methods of use in treatment ofand non-tubercular mycobacteria

Growing community of inventors

North Richland Hills, TX, United States of America

Thu Q Nguyen