Washington University

Thu Nga Bien-Ly

Mark S Dennis

Yin Sheng Zhang

Ryan Jefferson Watts

David Michael Holtzman

Adam P Silverman

Hong Jiang

Jing Guo

Fan Liao

The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

Anti-ApoE antibodies

The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

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South San Francisco, CA, United States of America

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