Pulsion Medical Systems Ag

Depuy International Limited

Depuy Products, Inc.

Fulsion Medical Systems Ag

Biosense Webster, Inc.

Johnson & Johnson Medical Gmbh

Depuy Orthopadie Gmbh

Thorsten M Burger

Yaacov Nitzan

Ulrich J Pfeiffer

Alec Paul Birkbeck

Yoav Lichtenstein

Alan Ashby

Noah Guyot

Michal Slomczykowski

Dudi Reznick

Andreas Becker

Harald Bornfleth

D Steven Block

Frank Foley

Marcellino Maheson

Magnus E Flett

Christian T&ouml;ns

Norbert Eder

Roger Oakeshott

Francois Urvoy

Joerg Haechler

Marcellino c/o Bupa Hospital Maheson

Alec Birbeck

Dave Cronin

Johanna Hayes

Alex Warnock

Doug Lemoine

Andrew Balaity

Simon Cawthan

Ian Revie

Christian Tons

Jurgen Mannss

A computer assisted surgery method and apparatus for determining a change in a property of a joint of a patient caused by an arthroplasty procedure is described. The relative position of a first bone and a second bone of the joint is determined with the joint in a first position. The position of a pre-operative center of motion of the joint relative to the first bone is determined. The position of the second bone relative to the pre-operative center of motion is determined using the relative position of the first and second bones. The position of a post-operative center of motion resulting from a prosthetic component to be used in the joint is determined. The position of the second bone relative to the post-operative center of motion is determined. Any change in the property of the joint. is determined from the difference between the position of the second bone relative to the pre-operative center of motion and the position of the second bone relative to the post-operative center of motion.

Surgical apparatus and procedure

A system and computer implemented method for use in determining the deviation of an intra-operative position of an orthopaedic implant from a planned position is described. The position of the orthopedic implant in the bone is defined by a plurality of implant position parameters. The distance of a plurality of anatomical features in a three dimensional model of the surface of the bone relative to a model of the implant at a first position is calculated. The first position corresponds to a first set of values for the implant position parameters. The distance of the plurality of anatomical features to a model of the implant at a second position in the bone is calculated. The second position corresponds to a second set of values for the implant position parameters, and the second position is different to the first position.

Intra-operative surgical plan changing

A method of performing a computer-assisted orthopaedic procedure includes securing a sensor support instrument to the patient's bone. A number of sensors are secured to the support instrument. A computer-assisted orthopaedic surgical instrument is also disclosed.

Method and apparatus for performing a computer-assisted orthopaedic procedure

An apparatus that continuously monitors the arterial pressure measured by a pressure sensor in an artery, which pressure is regarded as the reading Pao that approximately corresponds to the aortal pressure. In principle, the arterial pressure can be measured in the aorta, near the aorta, or in the arterial tree. To provide a second reading, the apparatus, via the input channel, continuously monitors the central venous pressure (CVP), which is regarded as the reading PIT that approximately corresponds to the intrathoracic pressure (ITP). The third reading is provided via the input channel as a reading Z which expresses the thoracic compliance. Via known algorithms of the pulse contour analysis, the apparatus calculates the stroke volume variation, using as the determining pressure the transmural pressure which is calculated according to the formulatransmural=()*PITThe cardiac volume responsiveness indicator (CVRI) is calculated for mechanical positive respiration according to the formulaCVRI=*(SVV/&#x394;CVP)or for spontaneous breathing according to the formulaCVRI=*(&#x394;CVP/SVV).

Apparatus for determining cardiovascular parameters

A system for the determination of quantifies relating to the circulatory system of a patient including a device for the non-invasive measurement of the qualitative variation over time of the local concentration of an indicator injected into the blood circulation system at a first position, the measurement taking place at a second position of the blood circulation system. An evaluating unit is provided, in which there is implemented an evaluating algorithm which transforms the qualitative variation into a quantitative variation over time of the local concentration of the indicator injected into the blood circulation system. For the purposes of the transformation, the condition is fulfilled that the cardiac output COdye calculable from the quantitative variation over time of the local concentration in accordance with a predetermined relationship is equal to an input value of the cardiac output COe, which has been determined by thermodilution measurement.

System and a computer program for the determination of quantities relating to the circulatory system of a patient

In a method, a device and a computer program for determining the blood flow in a tissue or organ region, the fluorescence intensity of an exogenous chromophore is measured as a function of time in the tissue region to be examined and from this the permeation rate of the chromophore is calculated, from which the blood flow can be derived.

Method, device and computer program for determining the blood flow in a tissue or organ region

A central venous cather ( ) is placed in the vena cava superior ( ) and equipped with a heating coil ( ) for emitting heat pulses in the immediate proximity of the distal end ( ) of the catheter ( ) in order to introduce travelling temperature deviations to the patient's circulation. The power transferred to the blood stream during emission of each heat pulse represents an input signal for modified thermodilution measurements. Each travelling temperature deviation is detected as a system response corresponding to an input signal, when it reaches an arterial catheter ( ) which additionally comprises a pressure sensor ( ) for measuring the local blood pressure in the arteria femoralis ( ) as a function of time. The computer ( ) has stored thereon an executable computer program for repeatedly determining a reference cardiac output value from a plurality of input signals and corresponding system responses by thermodilution curve evaluation methods and for determining from the blood pressure function hemodynamic parameters by pulse contour analysis methods using the most recent respective reference cardiac output value for quasi-continuous recalibration.

Apparatus, computer program, central venous catheter assembly and method for hemodynamic monitoring

A safety housing, into which an infrared laser light source is integrated together with the CCD camera, forms a compact unit for the determination of tissue perfusion. Rays from the infrared laser light source radiate the area of operation and indocyanin green, previously injected intravenously into the patient, is excited to fluorescence by the radiation, which is detected by the CCD camera.

Device for the determination of tissue perfusion and operative use thereof

A computer system ( ) is connected to an injection means ( ) to inject at a first place ( ) a bolus warmer or colder than patient's blood. The travelling temperature deviation thus introduced to the patient's vascular system ( ) passes the pulmonary circulation ( ), where an extravascular thermovolume ( ) may be present. When the temperature deviation reaches the second place ( ), where blood temperature is measured by a sensor device ( ) connected to the computer system ( ), it is recorded as Thermodilution Curve ( ), from which the computer system ( ) determines an extravascular thermovolume estimate. Depending on that result the computer system ( ) calculates a new amount of bolus to be injected by the injection means ( ). The higher the extravascular thermovolume estimate, the higher the new amount of bolus. The new travelling temperature deviation thus introduced to patient's vascular system ( ) eventually reaches the second place ( ), where it is recorded as an improved Thermodilution Curve ( ) from which cardio-vascular parameters of improved accuracy are derived by the computer system ( ).

Apparatus, computer system and computer program for determining a cardio-vascular parameter of a patient

The present invention relates to a method for determining the cardiac output of a subject by thermodilution measurements by providing a predetermined amount of thermal indicator in a blood vessel with the thermal indicator having a temperature different from the temperature of subject's blood, thus exhibiting an indicator temperature difference. By measuring the temperature of subject's blood at a second place downstream the cardiac output (CO) and the extravascular thermovolume can be determined as a function of the time for the thermodilution curve. As a function of the thermodilution curve the measurements of the amount of thermal indicator and/or thermal indicator volume temperature difference are adjusted to provide a more accurate determination of cardiac output.

Method to increase transpulmonary thermodilution cardiac output accuracy by use of extravascular thermovolume to control the amount of thermal indicator

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Munich, Germany

Thorsten M Burger