Sartorius Stedim Biotech Gmbh

Sartorius Stedim Switzerland Ag

Thorsten Adams

Gerhard Greller

Christian Grimm

Lars Boettcher

Mario Becker

Henry Weichert

Michael Bates

Eberhard Wuenn

Lars Böttcher

Fabian Tunzini

Rachel Delessert

Eberhard Wünn

Gregory Bremer

Clint Kukla

Matthias Bode

Jens Rupprecht

Franziska Faulstich

A sensor positioning system for a bioprocess engineering unit, wherein a container is provided for receiving a biological medium which, when installed, extends in the axial direction from an upper container end to a lower container end, wherein a holder is provided for holding the container when installed, wherein a sensor is provided for fixing to the container. A positioning aid device for positioning the sensor to be fixed is provided on the container, the positioning aid device has a positioning aid that can be applied directly to or near the container on the holder, which can be brought into different vertical positions and/or circumferential positions relative to at least one reference point provided on the container and/or holder, and the positioning aid device has a technical storage medium or analog print medium with an allocation list.

Sensor positioning system for a bioprocess engineering installation

The invention relates to a harvesting device () for harvesting a content of a bioreactor bag () and to a method for harvesting a content of a bioreactor bag (). The harvesting device () comprises: a first fixing device () for fixing one of the fixing portions () to the harvesting device (), a second fixing device () for fixing the other of the fixing portions () to the harvesting device (), a base (), and an adjusting device () coupling the first fixing device () and/or the second fixing device () to the base (). The adjusting device () is configured to selectively allow changing an arrangement of the first fixing portion () and/or the second fixing portion () relative to the base () or fixing the arrangement of the first fixing portion () and/or the second fixing portion () relative to the base ().

Harvesting device and method for harvesting the content of a bioreactor bag

A bioreactor for use on a moving platform including a bag. According to a first aspect, the bag defines a three-dimensional geometrical shape including at least one lower collecting vertex in which at least two edges of the geometrical shape meet at an angle not greater than 90°. The bioreactor further includes at least one port or sensor arranged in the vicinity of the collecting vertex. According to a second aspect, the bag defines a two-dimensional geometrical shape or a three-dimensional geometrical shape. The geometrical shape includes at least one edge, in which at least two faces of the geometrical shape meet at an angle not greater than 90°. A longitudinal port/sensor element is arranged along the edge and includes several ports and/or sensors. A bioreactor motion system including a moving platform and a bioreactor according to the first or second aspect. A method of performing a bioprocess.

Bioreactor for use on a moving platform, bioreactor motion system, and method of performing a bioprocess using a bioreactor motion system

A mixing device with a stirring element includes a container () for receiving fluids and/or solids, at least one rotatable stirring element () for mixing the fluids and/or solids, at least one bearing element for the support of the stirring element (). The stirring element () has at least one non-permanently magnetized element () so that the stirring element () can be put in a rotational movement by externally induced reluctance forces. A drive device having at least two pair of coils () through which current flows also is provided. A mixing device system includes the mixing device and the drive device. A method also is provided for driving a stirring element in a mixing device.

Mixing device with a stirring element, a drive device for driving a stirring element in a mixing device, a mixing device system and a method for driving a stirring element in a mixing device

A method is provided for measuring parameters of state of a fluid contained in a container (') that has a sensor carrier plate with plural sensors (S-S, S&#x2032;-S&#x2032;). Each sensor has a sensor head in operative contact with the interior of the container (&#x2032;) and in operative contact with an external control unit (). The external control unit () receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (&#x2032;) is assigned to each sensor (S-S, S&#x2032;-S&#x2032;) and is recorded in a manner that is accessible for the external control unit (). The external control unit () first accesses the activation data records (&#x2032;), then classifies the sensors (S-S, S&#x2032;-S&#x2032;) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.

Method for measuring a plurality of parameters of state of a fluid contained in a container

A method is provided for measuring status parameters of a fluid contained in a container (). The container () is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S-S) that are in operative contact with the internal chamber of the container () and connected for data exchange () with an external control unit () that receives and processes the measurement data from the sensors (S-S). The sensor plate also carries a temporarily inactive duplicate (D-D) of at least one of the sensors (S-S) that is activated if measurement data of the sensor (S-S) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit ().

Method for measuring a plurality of status parameters of a fluid contained in a container

The invention relates to a bioreactor for cultivating cells having a filter bag for separating culture fluid and cells, the filter medium of the filter bag having a degree of swelling of less than 1%. The bioreactor according to the invention is characterized by a high durability of the filter bag thereof.

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Goettingen, Germany

Thorsten Adams