Axagarius Gmbh & Co. Kg

Macherey, Nagel Gmbh & Co.

Thomas Zinn

Christoph Kirsch

Stefan Heymans

Manfred Sieber

Markus Meusel

Robert Zeidler

Florian Werner

Carolin Wagner

Klaus Möller

Claudia Bayard

The invention relates to a device for extracting nucleic acid from a formalin-fixed and paraffin-embedded sample comprising a hollow body having an inlet port and an outlet port and a filter layer arranged within the hollow body, wherein the device is characterized in that the filter layer has an oil repellency of at least grade 5 according to the test method by AATCC-118 (1997). The invention further relates to a method for extracting nucleic acids from a formalin-fixed and paraffin-embedded sample, and a kit comprising the inventive device.

Device having a filter layer and method for extracting nucleic acids from formalin-fixed and paraffin-embedded samples

The invention concerns a method for purifying biological macromolecules, e.g. nucleic acids or proteins, from starting materials, in which the macromolecules, contained in a biological solution, are purified on a chromatographic material, and in which endotoxins are partially or completely removed with the aid of a nonionic surfactant, which is characterized in that the surfactant and the biological solution are brought into contact immediately before or during the purification of the macromolecules on the chromatographic material.

Method for purifying biological marcromolecules, and chromatographic column for performing said method

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Düren, Germany

Thomas Zinn