American Home Products Corporation

Thomas W Pattison

John H Musser

Anthony F Kreft, Iii

John P Yardley

Stanley Charles Bell

Dieter H Klaubert

Richard W Rees

There are disclosed compounds of the formula ##STR1## wherein X is --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## Z is CR or N, where n=1; or Z is O,S, or NR, when n=0; R is hydrogen or loweralkyl;

Oxazole and thiazole naphthalenes as antiallergic agents

There are disclosed compounds of the formula ##STR1## wherein X is --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## Z is CR or N, when n=1; or Z is O, S, or NR, when n=0, R is hydrogen or loweralkyl;

Imidazolylmethoxy naphthalene compounds as antiallergic agents

There are disclosed compounds of the formula ##STR1## wherein X is --Ch.sub.2 CH.sub.2 --, --CH=CH--, ##STR2## Z is CR or N, when n=1; or Z is O, S, or NR, when n=0; R is hydrogen or loweralkyl;

Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as

There are disclosed compounds of the formula ##STR1## wherein Z is CR or N, when n=1; or Z is O, S, or NR, when n=0; n is 0 or 1; p is 1-10; R.sup.1 is hydrogen, loweralkyl, loweralkoxy or halo; R.sup.2 is hydrogen, loweralkyl, loweralkoxy or halo; or R.sup.1 and R.sup.2 taken together form a benzene ring; and the pharmaceutically acceptable salts thereof, and their use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like.

3(2-quinolinylalkoxy)phenols

The compounds of the formula ##STR1## in which R is hydrogen, halogen, alkyl, alkoxy, hydroxyl, nitro or cyano; and

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King of Prussia, PA, United States of America

Thomas W Pattison