Depuy Spine, Inc.

Depuy Synthes Products, Inc.

Depuy Acromed, Inc.

Edwards Lifesciences Corporation

Honda Motor Co., Ltd.

Rensselaer Polytechnic Institute

Medos International Sarl

Edwards Lifesciences Innovation Ltd.

Thomas V Doherty

Mark T Hall

David D Konieczynski

Steven C Ludwig

Niall Patrick Casey

Dale E Whipple

Bryan S Jones

Carl Lauryssen

David Mark Taylor

Alexander J Siegel

Alexander D Grinberg

Martin A Reynolds

Michael F O'Brien

William S Rosenberg

David M Selvitelli

James Kelly

Jonathan S Dordick

Tal Sheps

Eric D Kolb

Raymond F Murphy

Yoon Hee Kwon

Christopher J Olson

Mark C Boomer

Iain H Kalfas

Robert J Linhardt

Jun Takeuchi

Bradford Currier

Haim Brauon

Trevor John Simmons

Rakesh Kumar

Christopher James Chuah

Brian Patrick Murphy

Jeffrey W Schrieber

Minoru Miyauchi

Akifumi Otaka

Haynes Louis Harkey, Iii

Eran Hoffer

Jianjun Miao

Jong-Won Lee

Louis Harkey

Embodiments of the present disclosure include an implantable assembly for a native heart valve that includes a prosthetic heart valve and a braided support structure. The prosthetic valve includes a frame and prosthetic leaflets. The braided support structure has an inner braided layer and an outer braided layer. The outer braided layer is disposed over the inner braided layer. The outer braided layer is less porous to blood than the inner braided layer. The braided support structure defines a plurality of arms that are angularly spaced around the prosthetic heart valve such that each arm extends radially outwardly from the prosthetic heart valve. Other embodiments are also described.

Prosthetic heart valve docking assembly

In a representative embodiment, a method comprises implanting first and second inflatable bodies within an annulus of a native heart valve by securing the inflatable bodies to tissue of the native heart valve with sutures, and implanting a prosthetic heart valve between the inflatable bodies such that the prosthetic heart valve is retained within the annulus by the inflatable bodies.

The present invention generally provides a polyaxial fixation device having a shank with a spherical head formed on a proximal end thereof, and a receiver member having an axial passage formed therein that is adapted to polyaxially seat the spherical head of the shank. The polyaxial bone screw further includes an engagement member that is adapted to provide sufficient friction between the spherical head and the receiver member to enable the shank to be maintained in a desired angular orientation before locking the spherical head within the receiver member.

Polyaxial bone screw

In a representative embodiment, an implantable assembly for a native heart valve comprises a prosthetic heart valve and first and second inflatable bodies. The prosthetic heart valve can comprise a frame and prosthetic leaflets. The first inflatable body can comprise first and second end portions, wherein the first end portion is configured to be secured to tissue of the native heart valve at a first location, and the second end portion is configured to engage an outer surface of the prosthetic valve. The second inflatable body can comprise third and fourth end portions, wherein the third end portion is configured to be secured to tissue of the native heart valve at a second location, and the fourth end portion is configured to engage the outer surface of the prosthetic valve. The first and second inflatable bodies anchor the prosthetic valve within the annulus of the native heart valve.

Exemplary spinal fixation devices, systems, and method are provided for stabilizing vertebrae in a patient's spine. In one exemplary embodiment, methods and devices are provided for coupling one or more bone anchors, such as hooks, screws, etc., and/or one or more spinal fixation elements, such as spinal rods, cables, plates, etc. In certain exemplary embodiments, a cross connector is provided for connecting and stabilizing two bone anchors, a bone anchor and a spinal fixation element, or a bone anchor and bone.

Rod attachment for head to head cross connector

Systems and methods for decompressing a spinal canal

Bone screws and bone plates are provided that offer the surgeon the ability to either assemble the screws to the plate, or the plate to the screws, depending on the surgeon's preference and the patient's circumstances. The bone screws and bone plates of the present invention include a combination of geometric configurations that allow the screws and plates to fit together from different assembly directions. Additionally, the bone screws and bone plates can include material resilience features to allow expansion/contraction during assembly to allow bidirectional attachment to one another.

Resilient bone plate and screw system allowing bi-directional assembly

Embodiments of the invention provide a cellulose-sheathed carbon nanotube fiber. One aspect of the invention provides a sheathed nanotube fiber comprising: a carbon nanotube fiber; and a cellulose sheath extending co-axially along at least a first portion of a length of the carbon nanotube fiber. Another aspect of the invention provides a method of forming a sheathed carbon nanotube fiber, the method comprising: co-electrospinning a carbon nanotube fiber gel core within a cellulose solution sheath.

Cellulose sheathed nanotube fiber

Growing community of inventors

Irvine, CA, United States of America

Thomas V Doherty