Boston Scientific Scimed, Inc.

Scimed Life Systems, Inc.

Navilyst Medical, Inc.

Lifeshield Sciences LLC

Thomas V Casey, Ii

Janel L Lanphere

Robert F Rioux

Paul DiCarlo

Marcia S Buiser

Stephan P Mangin

Erin McKenna

Jianmin Li

William Joseph Shaw

George Bourne

Doreen Rao

Fergus Quigley

Steve Keenan

Kristoff Nelson

Barbara Bell

Greg Kapoglis

Zarouhi Minasian

Ernest J St Pierre

Bud Damiano

Ernest J Pierre

James Tobin

A particle includes a ferromagnetic material, a radiopaque material, and/or an MRI-visible material.

Embolization

Embolization, as well as related particles, compositions, and methods, are disclosed.

The present invention provides a sectional crimped graft that allows graft flexibility where required and limits the overall longitudinal extension. The present invention overcomes the disadvantage of fully crimped grafts by controlling the number of crimps per unit length, crimp height, crimp geometry and their location along the graft wall, dependent on the particular end-use application. In so doing, flexibility and elongation can be controllably tailored only in areas where significant anatomical angulation is present. It may also be useful in applications other than stent grafts such as surgical grafts for aortic and peripheral areas. Limiting the overall graft longitudinal extension also facilitates the deployment of the stent-graft into the blood vessel.

Sectional crimped graft

A magnetically steerable catheter system and method of using the system is provided. The system comprises an outer elongated, flexible member having a proximal and distal end, an inner elongated, flexible, member having a proximal end and a distal end, the inner member slidably disposed within the outer member. The system further comprises an electromagnet disposed on the distal end of one of the outer member and inner member, and a magnetically attractive element disposed on the distal end of another of the outer member and inner member. The magnetically attractive element is configured for magnetically interacting with the electromagnet to deflect the distal end of the inner member.

Magnetically steerable catheter assembly

A valve may include (a) a housing defining a valve lumen adapted for fluid connection with a lumen of a catheter; (b) a substantially conical valve member coupled to the housing and extending across the valve lumen to control flow therethrough; (c) a plurality of slits extending through the valve member and separated from one another circumferentially around the valve member; and (d) a ramp formed within a distal end of the valve lumen extending proximally from a distal tip of the valve member toward a ramp vertex separated from the distal tip by a predetermined distance.

Multi-slit high flow valve

Ferromagnetic particles and methods are disclosed.

Ferromagnetic particles and methods

Embolization, as well as related particles and methods, are described.

Embolic compositions and methods of delivering the compositions are disclosed. In some embodiments, the embolic compositions include a shape memory material.

Embolic compositions

Syringe systems for mixing and delivery of particles into the body are disclosed. In some embodiments, a mixing and delivery medical syringe system can include a barrel including first and second detachable sections, and first and second compartments communicable through a conduit.

Mixing and delivery of therapeutic compositions

A composition includes a plurality of particles. At least some of the plurality of particles include cross-linked polyvinyl alcohol and have a diameter of about 500 microns or less. The particles have a first average pore size in an interior region, and a second average pore size at a surface region. The first average pore size being greater than the second average pore size. The composition also includes a carrier fluid. The plurality of particles being in the carrier fluid.

Growing community of inventors

Grafton, MA, United States of America

Thomas V Casey, Ii