Gruenenthal Gmbh

Grunenthal Gmbh

Thomas Tzschentke

Klaus Schiene

Ulrich Jahnel

Ilona Steigerwald

Michel Hamon

Silvia Reinartz

Thomas Christoph

Stefan Oberboersch

Ruth Jostock

Corinna Sundermann

Michael Haurand

Sven Kühnert

Sven Kuehnert

Saskia Zemolka

Petra Bloms-Funke

Johannes Schneider

Dagmar Kaulartz

Stefan Oberbörsch

Jean De Vry

The use of tapentadol in the treatment of pain and/or pain chronification in a subject suffering from pain chronification and/or in the treatment of pain and inhibition of pain chronification in a subject suffering from pain and at risk of pain chronification, as well as the use of tapentadol for the treatment or inhibition of migraine.

Method of inhibiting chronification of pain

The use of tapentadol (i) in the treatment of pain in a subject suffering from depression and/or from anxiety, and/or (ii) in the treatment or the inhibition of depression or anxiety.

Use of tapentadol for inhibiting and/or treating depression and anxiety

Substituted bicyclic imidazo-3-yl-amine compounds are provided, as well as processes for the production thereof and pharmaceutical formulations containing these compounds. The use of these compounds for the production of pharmaceutical formulations and related methods of treatment are also provided.

Substituted bicyclic imidazo-3-ylamine compounds

Growing community of inventors

Aachen, Germany

Thomas Tzschentke