Schiapparelli Biosystems, Inc.

Spectrum Systems, LLC

Other

Schiaparelli Biosystems, Inc.

Thomas Tiffany

Bruce N Weyrauch

Norman Kelln

Robin Olson

Phillip Thayer

A system for high performance automated chemical analysis includes a video camera photometer with a computer-controlled interference filter wheel. A fluidics system delivers ultramicro sample and reagent volumes in the 0.05 to 5.0 microliter range to a supporting analytical media. The media is precisely positioned relative to the photometer by an x-y axis reaction media holder capable of accurate and precise positioning of the ultramicro reaction spots. The reaction media can consist of absorbent cellulose sample/reaction strips or microscopic sized multiple wells. A data and reduction system monitors multiple simultaneous reactions within a common test area of the analytical media to provide final quantitative reports. The method for conducting multiple chemical assays involves placing small volumes of sample/reagent combinations at discrete locations about a common test area on the analytical media and simultaneously measuring resulting optical changes at each discrete location.

Method and apparatus for conducting multiple chemical assays

Cuvette for a chemical analyzer

The automatic chemical analyzer includes a turntable adapted to hold a plurality of disposable cuvettes. An optical system adjacent to the turntable can perform analytical absorbance or fluorescence tests on the contents of each cuvette as they are rotated on the turntable. A sample/reagent tray is rotatably mounted about an axis parallel to the turntable axis. A common probe arm pivoted about a third parallel axis mounts a pipette that can be moved along an arcuate path intersecting a cuvette access station on the turntable and at least one container access station on the sample/reagent tray for transferring liquids as required by specific test procedures. A sample tube entry port is provided to support individual draw tubes that are manually delivered to the analyzer at a sample access station and to facilitate removal of samples by the pipette without exposing operating personnel to accidental contact with liquid materials in the draw tube.

Chemical analyzer

A disposable cuvette is molded of rigid transparent plastic resin that is impervious to liquids to be handled within it. The cuvette has a rectangular cross section. Identical side walls extend between upper and lower ends of each cuvette, the upper end being open for reception of liquids and the lower end being closed. Recessed optical surface areas at the lower end are perpendicular to one another for optical testing of the cuvette contents. An elongated cartridge holds a stack of abutting cuvettes to facilitate their handling.

Cuvette and cuvette cartridge for a chemical analyzer

Growing community of inventors

Spokane, WA, United States of America

Thomas Tiffany