Degussa Aktiengesellschaft

Evonik Degussa Gmbh

Aventis Research & Technologies Gmbh & Co Kg

Degussa Gmbh

Hoechst Aktiengesellschaft

Evonik Roehm Gmbh

Evonik Rohm Gmbh

Thomas Riermeier

Axel Monsees

Renat Kadyrov

Uwe Dingerdissen

Matthias Beller

Armin Boerner

Alexander Zapf

Jens Holz

Juan Jose Almena Perea

Harald Trauthwein

Juan Almena

Karlheinz Drauz

Armin Börner

Paul Knochel

Christoph Fleckenstein

Herbert Plenio

Vitali Tararov

Matthias Lotz

Carsten A Schneider

Wolfgang Anton Herrmann

Ralf Jackstell

Kai Rossen

Christian Meier

Holger Geissler

Jan Hendrik Schattka

Martin Hateley

Manfred Assmus

Florian Hermes

Kathrin Junge

Kathrin Nollenberger

Claudia Breindl

Karl-Josef Haack

Boris E Bosch

Claus Peter Reisinger

Thomas Dassinger

Wolf-Ruediger Krahnert

Stefan Klaus

Daniel Schichl

Odalys Esperanza Zayas Vargas

Juan José Almena Perea

Ilias Ilaldinov

Mark Sundermeier

Rene Leubert

René Leubert

The invention relates to a coating composition suitable for the coating of a pharmaceutical or nutraceutical dosage form, comprising a core comprising one or more pharmaceutical or nutraceutical active ingredients, wherein the coating composition is comprising at least 20% by weight of an enteric core/shell polymer composition derived from an emulsion polymerization process, wherein either the core of the core/shell polymer composition is formed by a water-insoluble, not cross-linked polymer or copolymer and the shell of the core/shell polymer composition is formed by an anionic polymer or copolymer or vice versa.

Coating composition suitable for pharmaceutical or nutraceutical dosage forms

The invention is directed to a phosphine compound represented by general formula (1) wherein R' and R&#x2033; independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R&#x2032; and R&#x2033; are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cpis a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines. 

Cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions

Disclosed herein are phosphine compounds represented by the general formula (4): and corresponding phosphonium salts represented by the general formula (4a): Also disclosed are processes for the preparation of these phosphines and phosphonium salts as well as their use as ligands in catalytic reactions.

The present invention is based on new ligand systems of the general formula (I). These ligand systems can be used advantageously in transition metal-catalyzed asymmetric syntheses. Likewise encompassed are the transition metal complexes thus prepared, a process for preparing the ligands and the use of the complexes in asymmetric synthesis. 

Unsymmetrically substituted phospholane catalysts

The present invention concerns novel bidentante optionally N-containing P-ligands of general formula (I) embracing a two-ring-system and processes for synthesizing them, transition metal complexes of these compounds and their use as catalysts.

Cycloolefin phosphine ligands and their use in catalysis

The present invention is directed to a process for preparing compounds of the general formula (I). Compounds of the general formula (I) are advantageous precursors for preparing phospholane catalysts, especially bisphospholane catalysts. The invention therefore likewise provides for the use of the substances in question for preparing these catalysts. 

Halophospholanes and their preparation

The present invention relates to ligands of the general formula (I). In addition, a process for the production thereof and the use thereof are demonstrated.

Bisphosphines as bidentate ligands

The present invention relates to novel nitrogen-containing monodentate phosphane ligands of formula (I) and to their use in catalytic reactions, especially in the improvement of haloaromatic compounds. 

Nitrogen-containing monodentate phosphines and their use in catalysis

(Hetero)aromatic are prepared from halogen-substituted (hetero)aromatic compounds in the presence of a base and a palladium catalyst having a nonpyrophoric monodentate phosphane ligand. The phosphane ligand structure includes two radical groups having a tertiary carbon attached directly to phosphorous and one radical group having a primary carbon attached to the phosphorous.

Process for the preparation of aromatic aldehydes

This application claims the benefit of German priority Application No. 10138140.9, filed on Aug. 9, 2001, and International Application No. PCT/EP02/08748, filed on Aug. 6, 2002. The invention relates to the production of amines by the reaction of aldehydes or ketones with ammonia or primary or secondary amines in the presence of a hydrogen-donor and the presence of homogeneous metal catalysts of the eighth sub-group under mild conditions.

Method for the production of amines by reductive amination of carbonyl compounds under transfer-hydrogenation conditions

The invention relates to novel chiral ligands of formula (I), the production thereof and the use of the same in catalytic reactions.

Chiral ligands, transition metal complexes thereof, and the catalytic use of the same

The invention relates to ferrocenyl ligands of general formula (II), the S,S-enantiomer or the R,R-enantiomer of the ferrocenyl ligands of formula (II) being enriched, and a method for producing such ligands.

Ferrocenyl ligands and method for the production of such ligands

The invention relates to bidentate organophosphorous ferrocenyl ligands containing ligands of formula (I), to their complex compounds and to their utilization in catalytic processes.

Ferrocenyl ligands and the use thereof in catalysis

The invention relates to the preparation of chiral or achiral amines by reaction of aldehydes or ketones with ammonia or primary or secondary amines in the presence of hydrogen and in the presence of homogeneous metal catalysts under mild conditions. Metal catalysts which can be used are complexes of late transition metals with chiral or achiral phosphorus-containing ligands.

Method for producing amines by homogeneously catalyzed reductive amination of carbonyl compounds

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Ober-Ramstadt, Germany

Thomas Riermeier