Hoffmann-la Roche Inc.

Teraview Limited

Thomas Rades

Hans Lengsfeld

Paul Hadvary

Hans Steffen

Joseph Tardio

Passchier Christiaan De Smidt

Rainer Alex

Phillip F Taday

Christine Feinle

Louise Ho

Michael Fried

Ingeborg Kraemer-Pittrof

J&uuml;rgen Gerhards

Yaochun Shen

Richard Oeschger

A method of performing dissolution analysis on a tablet, the method comprising: irradiating a tablet with radiation having at least one frequency in the range from 40 GHz to 100 THz; detecting radiation which has been transmitted through or reflected by the tablet; determining a parameter from the detected radiation indicative of the density of a coating layer of the tablet; and determining information about the dissolution characteristics of the tablet from said parameter.

Analysis apparatus and method

A pharmaceutical composition comprises at least one inhibitor of lipases, preferably an inhibitor of gastrointestinal and pancreatic lipases, such as orlistat, at least one surfactant, and at least one dispersant.

Pharmaceutical compositions containing lipase inhibitors

The present invention relates to compositions containing lipase inhibitors, e.g. orlistat, and the use of such compositions for treating, reducing or preventing functional dyspepsiaafter ingestion of meals, especially of fat containing or fat rich meals.

Pharmaceutical composition and method for treatment of dyspepsia

The present invention provides a process for encapsulating a shear sensitive fill mass which contains a pharmaceutical active agent or nutrient, characterized in that said fill mass is heated and subsequently cooled, prior to the encapsulation. The invention also provides capsules comprising shear sensitive fill material obtained by the said process which have a high and constant dissolution rate.

Process for encapsulating shear sensitive fill masses into capsules and capsules containing shear sensitive fill masses

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Dunedin, New Zealand

Thomas Rades