Other

Monarch Marking Systems, Inc.

Thomas R Wagner

Dale E Lamprecht, Jr

Debra A Stellwag

Gina M Craig

Stephen F Vatner

Yoshihiro Ishikawa

Charles C Homcy

The present invention relates to transgenic models of heart failure and, more particularly, to transgenic animals and methods for testing the usefulness of chemical compounds in treating or preventing heart failure. A transgenic mouse was developed wherein G,is selectively overexpressed approximately three-fold in the heart. Although steady state adenylyl cyclase activities are not altered, both the percent of agonist high affinity &bgr;-adrenergic receptors as well as the rate of catalyst activation are increased. In addition, physiological and pathological studies revealed that chronically-facilitated sympathetic stimulation causes adverse cardiac effects.

Transgenic model of heart failure

A barcode identification system is shown that includes a user operable personal computer for creating print jobs. The personal computer is coupled to a number of printers for printing the data for a job in a selected format on a record member such as a tag, label or the like. The system employs modular software. During the initialization of each of the software modules, the system determines whether the module includes a key identification that matches a system key and if not, the operation of the software module is limited to a demonstration mode if that mode is allowable. A data entry routine aids the user entering valid data for a selected format. In response to a print command, the data entered by the user is combined with the selected format to form a job. The job is then sent to a spooler which distributes the job to one of the barcode printers of the system.

Barcode identification system

A locking device for a valve to be used in conjunction with a lock having a hasp comprising a pair of detachably connected corresponding members that when assembled engage the flow valve to substantially prevent its movement. The members include a means to restrain relative twisting of the members, and a means for joining the members together with the lock wherein the hasp is sandwiched between said members.

Locking device for a valve

A locking device for a valve to be used in conjunction with a lock having an elongated barrel portion comprising a pair of detachably connected corresponding members that engage the flow valve to substantially prevent its movement. The members include covers, a means to restrain relative twisting of the members, and a means for joining the members together with the lock wherein a substantial portion of the barrel section of the lock is positioned between said members.

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Fairfield, OH, United States of America

Thomas R Wagner