Bayer Aktiengesellschaft

Thomas Philipps

Hilmar Bischoff

Peter Fey

Delf Schmidt

Rolf Angerbauer

Walter Hubsch

Dieter Petzinna

Gunter Thomas

Uwe Petersen

Thomas Schenke

Rainer Endermann

Andreas Krebs

Klaus-Dieter Bremm

Karl G Metzger

Burkhard Mielke

Stephan Bartel

Hans-Peter Krause

Klaus Grohe

Karl-Georg Metzger

Hans-Joachim Zeiler

Thomas Jaetsch

Franz Kunisch

Ingo Haller

Wilfried Schrock

Dieter Habich

Martin Scheer

Klaus Dieter Bremm

Heinz-Georg Wetzstein

Michael Stegemann

Walter H&uuml;bsch

Gu/ Nter Thomas

Jorg Petersen Von Gehr

J&ouml;rg Petersen Von Gehr

Walter Hu/ Bsch

Thomas Gunter

Peter Petzinna

Jorg Peterson-von Gehr

Substituted triols are prepared by reducing appropriately substituted carboxylic esters. The substituted triols can be used as active substances in medicaments.

Substituted triols

The invention relates to intermediate compounds for preparing novel quinolone derivatives- and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.

7-isoindolinyl-quinolone derivatives and 7-isoindolinyl-naphthyridone

The invention relates to novel quinolone derivatives and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.

7-isoindolinyl-naphthyridone derivatives, compositions and

Novel bactericidal pyrido[1,2,3-d,e,][1,3,4]benzoxadiazine derivatives of the formula (I) ##STR1## in which R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl or halogen,

Pyrido[1,2,3-D,E] [1,3,4]benzoxadiazine derivatives

For the treatment of lipoproteinaemia and arteriosclerosis, the new disubstituted pyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl or heteroaryl,

Polysubstituted pyridines useful for treating lipoproteinanaemia and

The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are linked to a .beta.-lactam antibiotic, to their salts, to processes for their preparation and to antibacterial agents containing these derivatives.

Quinolonecarboxylic acids

Disubstituted pyridines

The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a partly hydrogenated isoindolinyl ring, processes for their preparation and antibacterial agents and feed additives containing these compounds.

7-isoindolinyl-quinolone-carboxylic acid derivatives

Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines are prepared by reducing corresponding 4-phenyl-pyridone and 4-phenyl-2-alkoxypyridine derivatives. The substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines can be employed as active compounds in medicaments, in particular for the treatment of hyperlipoproteinaemia.

Substituted 4-phenyl-pyridones and 4-phenyl-3-alkoxypyridines

New substituted pyridines are prepared by reducing suitably substituted pyridine derivatives. The new substituted pyridines are suitable as active compounds in pharmaceuticals, in particular for the treatment of hyperlipoproteinaemia.

Substituted pyridines

Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula ##STR1## in which A, B, D and E can have varied meanings,

Substituted pyridines heptenoic acid derivatives, useful for treating

Intermediate imino-substituted pyridines of the formula ##STR1## in which R.sup.1 is optionally substituted aryl,

Certain intermediate imino-substituted pyridines

Substituted pyridyl-dihydroxy-heptenoic acid of the formula ##STR1## and its salts, if desired in an isomeric form, have a superior inhibitory action on HMG-CoA reductase and thus bring about a surprisingly good lowering of the cholesterol content in the blood.

Substituted pyridyl-dihydroxy-heptenoic acid and its salts

For the treatment of lipoproteinaemia and arteriosclerosis, the polysubstituted pridines of the formula ##STR1## in which R.sup.1 is optionally substituted furyl or thienyl,

7-[(2,6-dialkyl-4-furyl or

Growing community of inventors

Cologne, Germany

Thomas Philipps