Burroughs Wellcome Co.

Thomas Paterson

Hamish Christopher Wood

Alexander Stuart

8-Substituted pyrido[2,3-d]pyrimidines having activity against microorganisms which utilize de novo synthesis of riboflavin.

Pyrido-[2,3-d]pyrimidine compounds

A method of preparation of 2,4-diamino-5-benzylpyrimidines involving the reaction of a 2,4-diamino-5-substituted methyl pyrimidine, for example 2,4-diamino-5-hydroxymethylpyrimidine, with an appropriately substituted phenol.

Organic synthetic methods benzylpyrimidine derivatives

8-Substituted pyrido [2,3-d]pyrimidines having activity against microorganisms which utilize de novo synthesis of riboflavin.

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Larkhall, United Kingdom

Thomas Paterson