Medrad, Inc.

Bayer Healthcare LLC

Bayer Medical Care Inc.

Other

Thomas P Joyce

Michael A Spohn

Ralph H Schriver

William D Barlow

John A Haury

James Albert Dedig

Gerald W Callan

Herbert M Grubic

Michael A Riley

Richard G Critchlow

Ralph E Kopacko

Karen M Zelenski

Andreas Maihoefer

Roderick H Beaulieu

Jennie Kwo

Luis Alberto Pedraza

Jerry A Stokes

Susan Lynn Felix

John D Shearer, Jr

David M Griffiths

Joseph B Havrilla

Adam J Hahn

Salvatore J Dedola

Michael J Ehrenberger

Michael J Masters

William J Nolan

Joelle A Rudnick

Herb Grubic

Arthur E Uber, Iii

Alan D Hirschman

John Francis Kalafut

Mark Paul Jongewaard

Francis J Sciulli, Jr

Dennis P Hack

Frank A Lazzaro

Jonathan Robert Speicher

John Gardner

Christopher Scutt

William J Nolan, Jr

Julie Gulick

Linda M O'Meara

Michael J Ehrenberg

Gregory J O'Donnell

Ralph E Schriver

Jason A Zaperach

Patrick B Campbell

Mirza Hyder Hussain

A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes an automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe. The procedure includes the step of determining, using an electronic control device operably controlling the fluid injector system, whether a fluid injection procedure involving the syringe is impending. If the electronic control device determines that the fluid injection procedure is not impending, such that the automatic refill will not interfere with the fluid injection procedure, an automatic refill of the syringe is initiated.

Multi-fluid medical injector system and methods of operation

The control device is used to control delivery of fluids from a multi-fluid delivery system during a medical injection procedure. The fluid delivery system includes an injector used to deliver injection fluids to a patient. The control device is operatively associated with the injector for controlling discrete flow rates of injection fluids delivered to the patient. The control device includes first and second actuators associated with the manual control device, and an electronic substrate disposed within the manual control device and having a conductive pattern. The first actuator is operatively associated with the conductive pattern. The conductive pattern includes a plurality of predetermined digital values corresponding to discrete flow rates of injection fluids to be delivered by the injector. The second actuator is operatively associated with the electronic substrate and initiates output signals to the injector corresponding to desired mixture ratios of the injection fluids to be delivered by the injector.

Fluid mixing control device for a multi-fluid delivery system

The control device is used to control delivery of fluids from a multi-fluid delivery system during a medical injection procedure. The fluid delivery system includes an injector used to deliver injection fluids to a patient. The control device is operatively associated with the injector for controlling discrete flow rates of injection fluids delivered to the patient. The control device includes a housing, first and second actuators associated with the housing, and an electronic substrate disposed within the housing and having a conductive pattern. The first actuator is operatively associated with the conductive pattern. The conductive pattern includes a plurality of predetermined digital values corresponding to discrete flow rates of injection fluids to be delivered by the injector. The second actuator is operatively associated with the electronic substrate and initiates output signals to the injector corresponding to desired mixture ratios of the injection fluids to be delivered by the injector.

A system which includes a pressurizing mechanism to pressurize a fluid including a contrast enhancement agent for delivery to a patient and a control system in operative connection with the pressurizing mechanism. The control system includes a system to adjust control of fluid injection based upon a measurement of renal function of the patient.

Mitigation of contrast-induced nephropathy

Injector systems which include a syringe and a powered injector to inject a fluid into a patient are described. The powered injector includes a drive member, an energy source, at least one sensor for detecting energy from the energy source, and at least one contact member axially movable in the injector and in communication with the sensor. The syringe includes at least one indicator positioned at a predetermined position, such as on a rear surface of an attachment flange, which may transmit or reflect energy from the energy source to the sensor. The contact member may contact and be moved by the indicator when the syringe is attached to the powered injector, so that the energy detected by the sensor may be determined by the position of the indicator. The position of the indicator thereby provides information about the syringe configuration.

Injector system for encoding and sensing of syringe information

A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes a powered injector, a pressure jacket support, a syringe pressure jacket, and a syringe. The pressure jacket support includes a front plate and a rear plate. The rear plate is connected to the injector and the front plate is spaced from the rear plate and defines a slot. The syringe pressure jacket has a proximal end pivotally connected to the rear plate so that a distal end of the pressure jacket pivots relative to the front plate. The syringe has a syringe body with a distally extending discharge conduit. With the syringe disposed in a barrel of the pressure jacket, pivotal movement of the pressure jacket results in the distal end thereof pivoting toward the front plate to place the discharge conduit within the slot in the front plate.

The fluid injector system includes a source of injection fluid, a pump device, and a fluid path set in fluid connection with the source of injection fluid and the pump device. The fluid path set includes a drip chamber including an elongated body having a raised projection from substantially a top end to substantially a bottom end, the elongated body configured to receive and contain the injection fluid. A fluid level sensing mechanism is operably associated with a fluid control device, and includes a support for the drip chamber body, wherein the support is adapted such that the raised projection is in operational contact with a fluid level sensor associated with the support. The fluid level sensing mechanism is operable to transmit ultrasonic or light energy through the raised projection to be sensed by the fluid level sensor for sensing the injection fluid level in the drip chamber.

Drip chamber and fluid level sensing mechanism for a fluid delivery system

Injector systems including a syringe for use with a powered injector having a drive membre to inject a fluid into a patient having a first indicator positioned on the syringe at a predetermined position are described. The position of the first indicator may be associated with information about the syringe configuration. The first indicator can, for example, be positioned on a rear surface of an attachment flange of the syringe. The injector system includes sensors each having on and off states, and a shutter mechanism configured to place sensors in the on or off states. The state of each of the sensors provides a digital code corresponding to information on the syringe configuration.

A fluid injection system may include an injector, a syringe and an anti-rotation connection. The injector may have a drive piston having a plunger engaging end and the syringe may have a body and a plunger within the body. The plunger may have a proximal end with at least one coupling member adapted for engagement by the plunger engaging end. The anti-rotation connection may be formed by complementary anti-rotation elements associated between the proximal end of the plunger and the plunger engaging end of the drive piston to limit rotation of the plunger within the syringe body. The anti-rotation elements may include the at least one coupling member engaged in a radial groove defining at least one axial edge formed on the plunger engaging end to enable limited rotational movement of the plunger relative to the drive piston when the complementary anti-rotation elements are engaged.

Fluid injection apparatus having anti-rotation elements to limit syringe plunger rotation

Methods for capacitance volume correction in fluid-containing expandable bodies and associated fluid pathways are disclosed. The methods may be applied in fluid delivery systems used to supply fluids to patients during radiographic imaging procedures, including angiography. The methods control delivery of fluid to a downstream process, including providing a fluid-delivery expandable body and a pressurizing element in fluid communication with the downstream process, pressurizing the expandable body by moving the pressurizing element in the expandable body to reduce volume therein, determining an over-travel distance for the pressurizing element, and ceasing movement of the pressurizing element after allowing the pressurizing element to over-travel the over-travel distance to compensate for expansion of the expandable body under pressure. The expandable body may be a syringe and the pressurizing element may be a plunger disposed within the syringe. Movement of the pressurizing element may be controlled by an algorithm associated with a computer.

Methods for capacitance volume correction in fluid delivery systems

The fluid injection apparatus is adapted for use with a syringe and includes an injector and a pressure jacket associated with the injector. The injector includes a housing defining an opening for a drive piston extendable from the housing. The pressure jacket secures the syringe during an injection procedure. The pressure jacket has a distal end defining a syringe receiving opening for receiving the syringe, and a proximal end associated with the housing and generally aligned with the opening. The apparatus includes a syringe sensor adapted for engagement by the syringe when loaded into the pressure jacket. The housing may have an engagement tab adapted to engage an engagement recess in the pressure jacket to removably engage the pressure jacket with the housing. The apparatus may have one or more light sources associated with the housing for illuminating the syringe received in the pressure jacket.

Fluid injection apparatus having a syringe presence sensor

A syringe includes a body having a distal end, a proximal end and a center section therebetween, a plunger movably disposed in the body, and a hollow alignment flange for orienting and manipulating the syringe.

Syringe having a proximal end with an outward extending lip

A syringe includes a cylindrical body having a distal end and a proximal end, an injection section at the distal end and an expansion section at the proximal end, the injection section and the expansion section being connected by a cylindrical center section of relatively uniform outer diameter. The injection section includes a conical portion and an injection neck, the conical portion including an alignment flange extending outward from at least a portion of the conical portion. The syringe further includes a plunger movably received in the body and having a coupling end with a pair of flexible coupling members defining a slot therebetween for engaging a drive piston of an injector, the slot being substantially aligned with the alignment flange such that the alignment flange provides an indication of the orientation of the slot, the plunger seated for storage in the expansion section. A syringe has a reduced wall thickness at the expansion section such that an inner diameter of the expansion section is larger than the inner diameter of the center section for allowing the expansion section to expand under radial outward force exerted by the plunger.

Syringe with alignment flange and expansion section with reduced wall thickness

Growing community of inventors

Wilkins Township, PA, United States of America

Thomas P Joyce