Archer Daniels Midland Company

Iowa State University Research Foundation, Inc.

University of Kansas-ku Medical Center Research Institute

T.en Process Technology, Inc.

Other

Novozymes A/s

Archer Midland Company

Thomas P Binder

Ahmad K Hilaly

Paul D Hanke

Charles Abbas

Leif Solheim

John Glenn Soper

Mark G Matlock

Kyle E Beery

Mitchell J Schultz

Bala Subramaniam

Aragula Gururaj Rao

Perry H Doane

Paul D Bloom

Louis A Kapicak

Daryle Hadley Busch

Steven J Furcich

Kevin M Moore

Michael J Cecava

David P Holzgraefe

William A Torello

Andrew M Danby

Inmok Lee

Naveen Sudharsan

John Less

Alexandra Sanborn

Hungming J Liaw

Chi-Cheng Ma

Thomas V Gottemoller

James A McClain

Prashant Iyer

Armindo Ribiero Gaspar

ChiCheng Ma

Doug Geier

Jill S Bradshaw

Anne M Rammelsberg

James Croonenberghs

Armindo Ribeiro Gaspar

Yasufumi Yamamoto

Joseph Michael Stevens

Robert M Logan

Robert Duane Sandage

Philip C Fass

Stacia L Swisher

Daniel G Dueppen

Wuli Bao

Kris N Mani

Thomas Wiegand

Ming-Der Wang

Lowell J Sievers

Scott Bloomer

Donald K Hadden

Julian R Silverman

Steffan Green

Lori E Wicklund

Mitchell Jo Schultz

Naveen S Sudharsan

Paul Hanke

Daryle Busch

Leif P Solheim

James A Mcclain

John G Soper

Lisa M Pfalzgraf

Daniel Dueppen

Mitchell Schultz

G Soper John

Integrated processes are disclosed for the catalytic conversion of carbohydrate to ethylene glycol and/or propylene glycol using a homogeneous, tungsten-containing retro-aldol catalyst. In these processes, the carbohydrate is subjected to retro-aldol conversion and hydrogenation to provide a reaction product containing ethylene glycol and/or propylene glycol, other reaction process including organic acids, itols and tungsten species. Ethylene glycol and propylene glycol are separated from the reaction product for purification, and at least a portion of the remaining fraction is subjected to ion exclusion chromatography to provide an eluant containing tungsten species and a subsequent eluant containing organic acids and a substantially reduced concentration of tungsten species. At least a portion of the eluant containing tungsten species can be recycled for reuse directly or with intervening unit operations to enhance the catalytic activity of the tungsten species. The organic-containing fraction can be subjected to one or more unit operations to provide salable products or subjected to selective hydrogenolysis to lower glycols.

Processes for making ethylene glycol and/or propylene glycol from aldose- and/or ketose-yielding carbohydrates with integrated tungsten catalyst recovery

Methods of forming lignin prepolymers are provided. In an embodiment, such a method comprises adding an acid to an ozonized reaction mixture, the ozonized reaction mixture comprising ozonized lignin having a backbone, and aromatic monomers cleaved from a lignin, under conditions to react the cleaved aromatic monomers with the backbone of the ozonized lignin to form a lignin prepolymer. The methods may further comprise using the lignin prepolymer to form a lignin resin.

Methods for forming lignin prepolymers and lignin resins

Described herein is a method of adjusting the composition of a chromatography product to achieve a target enriched proportion of a desired component from an input feed having a lower proportion of the desired component using simulated moving bed ('SMB') chromatography wherein the eluent for the SMB apparatus may comprise the very input feed being enriched. The method is exemplified by enriching a high fructose corn syrup from a 42% fructose syrup to a 55% fructose syrup without substantially reducing the dissolved solids concentration of the 55% syrup relative to the input 42% syrup. The 42% syrup is also used as the eluent for the SMB apparatus and may be reconstituted from the raffinate stream by passing the raffinate stream over a glucose isomerase column alone or in combination with a dextrose feed. The method reduces water usage and saves energy by minimizing the need for evaporation to obtain a 55% fructose syrup with a high dissolved solids content.

Method for adjusting the composition of chromatography products

A process is described for making acrylic acid from dextrose, which comprises fermenting dextrose; removing solids from the resulting fermentation broth; removing lactic acid from the clarified broth by extraction into an organic solvent; separating out the lactic acid-loaded organic solvent while recycling at least a portion of the remainder back to the fermentation step; reacting the lactic acid with ammonia to provide a dehydration feed comprising ammonium lactate while preferably recycling the organic solvent; carrying out a vapor phase dehydration of the ammonium lactate to produce a crude acrylic acid product; and purifying the crude acrylic acid by distillation followed by melt crystallization, chromatography or both melt crystallization and chromatography.

Process for making acrylic acid from dextrose

The present invention relates enzyme composition comprising a cellulolytic preparation and an acetylxylan esterase (AXE); and the used of cellulolytic enzyme compositions for hydrolyzing acetylated cellulosic material. Finally the invention also relates to processes of producing fermentation products from acetylated cellulosic materials using a cellulolytic enzyme composition of the invention.

Cellulolytic enzyme compositions and uses thereof

Described herein are small peptide domains and consensus sequences that bind small target molecules of industrial importance, e.g., metals such as nickel, &#x3b2; carotene, and isoflavones such as genistein. Also described are fusion proteins containing such binding domains fused to proteins or to peptide domains like GST or CBD that bind other ligands and can be used to immobilize the target binding domain on a support. One class of fusion proteins that is useful in industrial settings are fusions that contain concatemers of target binding domains, which increases the binding equivalents per molecule.

Peptide domains that bind small molecules

Peptide domains that bind small molecules of industrial significance

Anhydrous methods of fractionating corn grain that do not require the use of water but rather depends on use of organic solvents are described. The methods include contacting whole grain corn flour with a at least one organic solvent selected from the group consisting of a C1-C6 alcohol, ketone, ester or furan to form an admixture having no more than 15% w/w water. The admixture is separated into i) a solids fraction enriched with corn fiber and protein and 2) a liquid organic slurry comprising suspended starch, dissolved corn oil and the organic solvent. The starch is separated from the first organic slurry to obtain a solvent extracted solid starch fraction and a clarified organic solution. The clarified organic solution which contains dissolved oils is retained and may be evaporated to obtain corn oil that can be further refined.

Anhydrous corn processing

A process is provided for chromatographically separating propionic acid from acrylic acid. By means of the inventive process, a reduced propionic acid content acrylic acid product is enabled having a propionic acid content comparable to acrylic acid products from the conventional two stage oxidation of propylene, but wherein the acrylic acid has been produced with a higher propionic acid content by alternative methods.

Separation of propionic acid from acrylic acid

A process for purifying a filtered fermentation broth of succinic acid is described. The process involves separating succinic acid from the other organic acids and salts in a raw filtered broth using a non-functionalized chromatographic resin. The operation can be run either as an isocratic elution to yield free succinic acid, or as a gradient or binary elution to produce succinate salt.

Purification of succinic acid from fermentation broth on non-functionalized chromatographic resin

A modification is described of a dry grind process for producing ethanol and other co-products from whole grain, whereby the mash is thermochemically treated by cooking the mash in the presence of an organic acid. The organic acid effectively hydrolyzes both the starch and hemicellulosic components in the milled corn to provide fermentable sugars from both the endosperm and other parts of the kernel, without, however, also producing fermentation-inhibiting levels of other known products of the acid hydrolysis of hemicellulosic materials, such as hydroxymethylfurfural (HMF) and furfural. Further, the organic acid is able to solubilize both the starch and the more recalcitrant hemicelluloses while only partially hydrolyzing the same, so that most of the starch and hemicelluloses are hydrolyzed to oligomers and the amount of chemically labile and reducing sugars is kept sufficiently low as to also not appreciably interfere with the fermentation to ethanol.

Grain milling process

A process is disclosed for making dehydration products from an aqueous sugars solution including pentoses, hexoses or both, for example, an aqueous high fructose corn syrup solution, or from an aqueous solution of one or more of the alcohols of such pentoses and hexoses, for example, from an aqueous sorbitol solution, by an acid-catalyzed dehydration using substituted sulfonic acids solubilized in the aqueous sugars or sugar alcohols solution.

Processes for making sugar and/or sugar alcohol dehydration products

A method for increasing ozone concentration in a liquid can include: providing a gas having ozone; introducing the ozone-containing gas into a liquid, wherein the liquid and ozone combination has a temperature between about 0.8 and about 1.5 times the critical temperature of ozone; and increasing isothermally, the pressure of the ozone-containing gas above the liquid to about 0.3 to about 5 times the critical pressure of ozone so as to increase the ozone concentration in the liquid. The temperature is expressed in absolute units (Kelvin or Rankin). The method can be used for removing ozone from a gas or for purifying ozone. The liquid having a high ozone concentration can be used for ozonolysis of a substrate.

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Decatur, IL, United States of America

Thomas P Binder