Leland Stanford Junior University

Biomet Manufacturing Corporation

The United States Government As Represented by the Department of Veterans Affairs

Thomas P Andriacchi

Philipp K Lang

Eugene J Alexander

Daniel Steines

Sandy A Napel

David Scott Fisher

Jennifer C Erhart-Hledik

Jorge O Galante

Stefano Koenig Corazza

Lars Mündermann

Aspects of the cutaneous stimulation devices include a cutaneous stimulation module and a cutaneous association element configured to stably associate the module with a skin location. The cutaneous stimulation module may be an active or passive module. Also provided are methods of using the devices, e.g., in rehabilitation and/or pain mitigation applications.

Method of treating pain

Cutaneous stimulation devices are provided. Aspects of the devices include a cutaneous stimulation module and a cutaneous association element configured to stably associate the module with a skin location. The cutaneous stimulation module may be an active or passive module. Also provided are methods of using the devices, e.g., in rehabilitation and/or pain mitigation applications.

Cutaneous stimulation devices and methods of using the same

A knee replacement system, and a method for supplying and implanting a knee replacement system, for enabling natural knee movement in a leg in a patient, including: a medial femoral component having a medial femoral articulating surface with a sagittal plane profile including four medial femoral arcuate portions scaled by a first femoral scaling factor; a lateral femoral component having a lateral femoral articulating surface with a sagittal plane profile including four lateral femoral arcuate portions scaled by a second femoral scaling factor; a medial tibial component having a medial tibial articulating surface that articulates with the medial femoral articulating surface and includes a first raised medial edge that increases in width in an anterior direction; and a lateral tibial component having a lateral tibial articulating surface that articulates with the lateral femoral articulating surface and includes a second raised medial edge that increases in width in the anterior direction.

Knee replacement system and method for enabling natural knee movement

A method of implanting a knee replacement system in a leg with a femur and a tibia of a patient can include, implanting a femoral component onto a condyle of the femur and placing a trial tibial component on a tibial plateau of the tibia. The tension of a posterior cruciate ligament can be adjusted. The tension of an anterior cruciate ligament can be adjusted. The posterior position of the trial tibial component can be adjusted. The knee condition at toe off onset can be simulated during walking.

Methods are disclosed for assessing the condition of a cartilage in a joint and assessing cartilage loss, particularly in a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. The amount of cartilage tissue that has been lost, for example as a result of arthritis, can be estimated.

Joint and cartilage diagnosis, assessment and modeling

The therapeutic system of the preferred embodiments includes a foot platform having a lateral segment and a medial segment. The foot platform is coupled to the foot of the patient and supports the body force of the patient. The foot platform functions to move the foot from an equilibrium position to an activated position. The transition of the foot between equilibrium position and activated position, preferably occurs substantially instantaneously once the foot platform supports greater than substantially half of the body force.

Foot platform

Methods are disclosed for assessing the condition of a cartilage in a joint, particularly a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

Assessing the condition of a joint and preventing damage

Therapeutic system and method for altering the gait of a patient

Methods are disclosed for assessing the condition of a cartilage in a joint, particularlyina human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

Assessing the condition of a joint and devising treatment

Methods are disclosed for assessing the condition of a cartilage in a joint, particularly in a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

A markerless motion capture system is provided for measurements accurate enough for biomechanical, clinical, sport, entertainment, animation, game and movie, design, ergonomics, surveillance applications. The system has multiple cameras distributed around a viewing volume. The cameras allow for the creation of three-dimensional mesh representations of an object dynamically moving within the viewing volume. A model of the object that incorporates specific morphological and kinematic model information (including soft joint constraints) is then matched to the captured three-dimensional mesh representations. The matching routine aims to embed the model into each of the three-dimensional representations using (i) iterative closest point or simulated annealing algorithms and (ii) using soft joint constraints. This unique combination of routines offers a simple, time-efficient, accurate and thus more meaningful assessment of movements. The system further offers feasibility of accurately and precisely measuring three-dimensional kinematics of the dynamically moving object or human.

Growing community of inventors

Los Altos Hills, CA, United States of America

Thomas P Andriacchi