New Chapter Inc.

Other

The University of Texas System

The Cleveland Clinic Foundation

Thomas Newmark

Paul Schulick

Robert A Newman

Aaron Katz

Bharat B Aggarwal

Mladen Golubic

Peiying Yang

Aaron 61 FtWashington Ave Herbert Irving Katz

The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachidonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.

Methods for modulating eicosanoid metabolism

The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.

The inventive subject matter relates to methods for treating glioblastoma, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric,, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1&#x3b1;, interleukin-1&#x3b2;, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.

Methods for treating glioblastoma with herbal compositions

The inventive subject matter relates to methods for treating prostate cancer, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric,, rosemary, green tea, huzhang, Chinese goldthread, and barberry.

The inventive subject matter relates to methods for treating oral cancers, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric,, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The inventive subject matter further relates to methods for modulating gene expression of genes selected from the group consisting of interleukin-1&#x3b1;, interleukin-1&#x3b2;, heme oxygenase 1, aldo-keto reductase family 1, member C2, colony stimulating factor 3, leukemia inhibitory factor, heat shock 70 kDa protein, and combinations thereof, by administration of an effective amount of said compositions.

Methods for treating oral cancers with herbal compositions

Methods for treating prostate cancer with herbal compositions

The inventive subject matter relates to methods for treating prostatic intraepithelial neoplasia, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary, turmeric, oregano and ginger; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, ginger, turmeric,rosemary, green tea, huzhang, Chinese goldthread, and barberry.

Methods for treating prostatic intraepithelial neoplasia with herbal compositions

A method is provided for effecting smoke detoxification in a human by using a composition that is made of effective amounts of supercritical extract and hydroalcoholic extract of turmeric.

Composition and method for smoke detoxification

An orally administered composition capable of reducing inflammation in animals, preferably humans, while promoting sleep for such animals, contains a therapeutically effective amount of a post-supercritical carbon dioxide hydroalcoholic extract of ginger, therapeutically effective amounts of supercritical carbon dioxide extracts of hops, chamomile, ginger, valerian and melissa; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellaria baicalensis, chamomile and hops. The composition is preferably orally administered on a daily basis for at least about 4 weeks.

Anti-inflammatory, sleep-promoting herbal composition and method of use

An orally or topically administered composition capable of reducing inflammation in animals, preferably humans, suffering from inflammation, contains a therapeutically effective amount of a post-supercritical carbon dioxide alcoholic extract of ginger; therapeutically effective amounts of supercritical carbon dioxide extracts of rosemary, turmeric, oregano and ginger (preferably certified organic ginger); and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellariae baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The composition is preferably orally administered on a daily basis for at least about 4 weeks.

Growing community of inventors

St. Louis, MO, United States of America

Thomas Newmark