University System of Maryland

Thomas McAvoy

Warren D D'Souza

William Regine

Kathleen Malinowski

X Cedric Yu

Mohan Suntharalingam

A system and method for indirectly monitoring the position of a target inside a body is disclosed. The method includes generating position data associated with one or more surrogate devices and predicting a location of the target from the position data based on a target position model that establishes a relationship between an actual location of the target and the position data of the one or more surrogate devices. The method also includes determining that the predicted location of the target deviates from the actual location of the target when an analysis of an error prediction model results in a confidence threshold being exceeded.

Method for monitoring the accuracy of tissue motion prediction from surrogates

Techniques for improving treatment delivered to a target site in a patient include delivering a treatment from a treatment delivery device to a target site in a patient supported by a patient support structure. During the delivery of treatment, a state of the patient is measured to produce real-time measurement data. Measuring the state is non-invasive; and the measured state is a correlated surrogate for position of the target site. Compensating movement data is determined based on the real-time measurement data to cause the target site to maintain a particular spatial relationship with the treatment delivery device. Either the treatment delivery device, or the support structure, or both, are moved based on the compensating movement data. When the delivery device alone is moved, the correlation between measured state and target site is based on partial least squares applied to pre-treatment measurements of both.

Growing community of inventors

Ellicott City, MD, United States of America

Thomas McAvoy