Sanofi-a Ventis Deutschland Gmbh

Sanofi

Pa Knowledge Limited

Thomas Mark Kemp

Matthew Ekman

Simon Francis Brereton

Rosie Burnell

Carsten Mosebach

Hugo Revellat

Louise Hodgson

William Timmis

Douglas Ivan Jennings

Uwe Dasbach

Yannick Hourmand

Timothy Donald Barrow-Williams

Jim Bradford

Stefan R Taal

Marc Schader

Peter Scudamore

George Sykes

Haiming Wu

Daniel Auernhammer

David Morrison Russell

Paul Edward Jansen

Timothy Denyer

Florian Schauderna

Rosemary Louise Burnell

Kai Scheinert

Andrew Peter Scudamore

Frederick Harrison

George Edward Sykes

Michael Mayer

Andrew Labat-Rochccouste

Robbie Wilson

Sarah Bielby

Alex Zuyev

Tim Schuller

Douglas A Jennings

Ryan Anthony Mcginley

David Jonathan Townley Whitaker

Michael Noble

Andrew Labat-rochecouste

Craig Harvey Nelson

Chris Rosier

The disclosure relates to a drug delivery device including a plunger disposed within a case and an audible indicator that comprises a resilient element. The plunger is slidable from a proximal position to a distal position within the case and the resilient element is in a first configuration when the plunger is in the proximal position, such that the resilient element is deflected radially outwards to a second configuration during movement of the plunger from the proximal position towards the distal position. The resilient element moves from the second configuration towards the first configuration when the plunger moves towards or reaches the distal position, thereby generating an audible and tactile signal.

Drug delivery device

An autoinjector includes a case, a needle shroud telescopically coupled to the case, a carrier slidably arranged in the case, a collar rotatably and slidably disposed in the case and coupled to the needle shroud and the carrier, and a trigger button operably coupled to the carrier. The case includes a rib. The needle shroud is movable between a first extended position, a retracted position, and a locked second extended position. The carrier is adapted to hold a medicament container and movable from a first axial position to a second axial position relative to the case. The carrier abuts the rib in the first axial position and the needle shroud is in the first extended position and disengages the rib when the needle shroud is in the retracted position and the trigger button is pressed to advance the carrier to the second axial position.

Autoinjector

An auto-injector includes a housing, a sleeve, a plunger rod, and a drive spring. The sleeve is sized to receive at least a distal portion of a syringe. The syringe is substantially symmetric about at least two planes that are perpendicular to one another. The plunger rod has an axially-extending portion that is substantially symmetric about the at least two planes, and a flange. The auto-injector has (i) a first state in which at least two axially-extending resilient arms hold the plunger rod in a first position relative to the sleeve to prevent a medicament from being dispensed from the syringe and (ii) a second state in which the at least two axially-extending resilient arms are allowed to deflect radially inward to release the plunger rod from the sleeve to allow the medicament to be dispensed from the syringe.

Auto-injector

An injection device comprising a housing and a cap at a distal end of the housing, the cap comprising: an outer member; an intermediate member disposed within the outer member, at least one of the intermediate member or outer member being rotatable relative to the other of the intermediate member or outer member; and, an inner member disposed within the intermediate member, and coupled to at least one of the outer member and the intermediate member, the inner member being configured to engage a needle shield in the housing. The injection device further comprises a lifting mechanism to reduce a force required to remove the cap from the housing, the lifting mechanism comprising at least one axially-inclined portion in engagement with at least one lifting portion such that rotational movement of the outer member or intermediate member is converted into an axial movement of the inner member from the housing.

Injection device

A drug delivery device includes a case adapted to hold a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament from the medicament container, at least one feedback mechanism that is in operative connection with the plunger. The feedback mechanism comprises a collar, a control spring biasing the collar in a distal direction, a needle shroud, operatively axially abutting the collar in a first coupled state and prevented from axially decoupling the collar by the plunger in its proximal position The plunger, when approaching the distal position during movement from the proximal position towards the distal position, is adapted to allow axial decoupling of the needle shroud from the collar, allowing for a limited axial movement of the collar relative to the needle shroud until the collar axially abuts the needle shroud in a second coupled state.

Drug delivery device with feedback mechanism

A drug delivery device includes a case adapted to hold a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament from the medicament container, at least one feedback mechanism that is in operative connection with the plunger. The feedback mechanism comprises a collar, a control spring biasing the collar in a distal direction, a needle shroud, operatively axially abutting the collar in a first coupled state and prevented from axially decoupling the collar by the plunger in its proximal position. The plunger, when approaching the distal position during movement from the proximal position towards the distal position, is adapted to allow axial decoupling of the needle shroud from the collar, allowing for a limited axial movement of the collar relative to the needle shroud until the collar axially abuts the needle shroud in a second coupled state.

An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Plunger rod for an auto-injector

Auto-injector methods

Growing community of inventors

Ashwell, United Kingdom

Thomas Mark Kemp