Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Georg-august-universitat Gottingen Stiftung Offentlichen Rechts, Universitatsmedizin

Thomas Mager

Ernst Bamberg

Phil Wood

David Lopez De La Morena

Tobias Moser

The invention relates to mutant light-inducible ion channels having improved properties as compared to the parent channel, nucleic acid constructs encoding same, expression vectors carrying the nucleic acid construct, cells comprising the nucleic acid construct or expression vector, and their respective uses, as well as non-human animals comprising the mutant light-inducible ion channel, the nucleic acid construct or the expression vector as disclosed herein.

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Frankfurt-am-Main, Germany

Thomas Mager