Molecular Devices Corporation

Abbott Laboratories Corporation

Mds Analytical Technologies (us) Inc.

Arcturas Bioscience, Inc.

Thomas L Smith

Edward D Verdonk

Grischa Chandy

Thomas Michael Baer

Calvin Y Chow

Robert H Reamey

Nicholas F Talesfore

Evan Francis Cromwell

Rick T Smethers

Peter A Holst

Vladimir J Drbal

Jonathan Briggs

Michael M Lacy

Suresh N Mehta

Derrick A Richardson

Timothy Arthur Floto

Derek Pai

Steven T Kunitake

Lev Leytes

Jorge Monteon

Gregory L Kirk

Debra A Ross

Joseph McArdle

George Pontis

A plenum assembly configured for electrophysiology assays, such as patch clamp techniques, includes one or more ground electrode assemblies. The ground electrode assemblies are individually removable from a plenum base of the plenum assembly in a non-destructive manner, and may be reinstalled in the plenum base in a manner that reestablishes electrical contact with ground circuitry without requiring soldering or other additional steps. A rejuvenating apparatus is provided for rejuvenating one or more ground electrode assemblies removed from the plenum base.

Replaceable ground electrode for electrophysiology, electrode rejuvenating apparatus, and related methods and systems

System, including methods and apparatus, for sample processing. In exemplary embodiments, the system comprises a plurality of devices to perform a protocol on sample holders supporting samples, and also comprises a control system that coordinates operation of the plurality of devices, such that the protocol is performed automatically. Each device of at least two of the plurality of devices may have one or more status lights configured to display a plurality of different visual indicators each indicating a different status of the device. The at least two devices may utilize a same indicator scheme as one another for each different status indicated by the visual indicators. In some embodiments, the indicator scheme is user-configurable. In some embodiments, the one or more status lights of at least one device are provided by one or more recessed light-emitting strips.

Sample-processing system with status lights

Scientific instrument

This relates to filter columns for isolating nucleic acids, particularly at small elution volumes. The filter column is adapted for stable placement within the upper portion of standard plastic collection tubes of various sizes. The body of the filter column has a number of surfaces to accommodate placement within variously sized collection tubes. The filter column contains nucleic acid-specific filter which can be located at alternate regions within the filter column, providing different filter surface areas and loading volume capacities using the same column body. The filter column has an opening on an upper end adapted to be sealed by a cap. A method for recovering nucleic acids using such filter column is also provided.

Low volume filtration column devices and methods of filtering therewith

A device and method for the temperature control, concentration, volume measurement and transport of microfluidic volumes are provided. The device includes one or more heating elements having a resistive material that varies with temperature. The heating elements are formed into a laminar body that may be formed into a variety of geometries and/or easily married to a second body including micro-well plates, micro-centrifuge tubes and microfluidic circuits.

Apparatus and method for heating microfluidic volumes and moving fluids

A coupler for connecting a drive shaft to a driven member and accommodating a substantial misalignment between the drive shaft and the driven member, while minimizing audible noise and vibration. The coupling includes a hollow core nest element having a plurality of slots formed in one end, two substantially identical elongate body elements, and a plurality of spring elements. Each elongate body element has two ends, a first end being adapted to couple with either the drive shaft or the driven member, and a second end that includes a plurality of posts that engage the slots of the hollow core nest. An aperture in the hollow core nest is larger than the diameter of the elongate bodies, allowing for the components to move radially relative to each other to accommodate for any offset and misalignment between the longitudinal axes of the drive shaft and the driven member, while the spring elements ensure that the components positively contact one another to reduce audible noise that is otherwise produced by loose fitting components. In one embodiment, a spring element is integrally formed in the slots of the hollow core nest, such that the posts of the body elements are held in engagement with sides of the slots by the spring elements. This embodiment includes an end cap that prevents the posts from becoming disengaged from the slots. Another embodiment employs helical coil springs mounted externally around the hollow core nest.

Universal style coupling

This invention encompasses a work station for conducting assays which comprises filtering assembly, a slide reading assembly, and a slide with a porous filter membrane wherein the slide has a means for aligning the slide within the filter assembly to filter reagents on predetermined portions of the porous filter membrane and also to position the slide in the slide reading assembly so that detection will occur in those same predetermined locations.

Analytical work station

Growing community of inventors

Campbell, CA, United States of America

Thomas L Smith