Degussa Aktiengesellschaft

Huels Aktiengesellschaft

Degussa-huels Aktiengesellschaft

Thomas Kalz

Karlheinz Drauz

Manfred Kaufhold

Wolfgang Kleemiss

Oliver Meyer

Manuela Imig

The present invention is directed to a method for producing amino acids by reacting halogenated carboxylic acid ester (haloacid esters) with a metal cyanate in the presence of an alcohol and by subsequent acidic saponification of the urethane carbonic acid formed. The method is characterized by the metal cyanate being placed at an elevated temperature in an organic solvent and the other reactants being continuously charged into the mixture over a defined time period.

Method of producing amino carboxylic acids

Cyanoacetamide is prepared without additional catalyst by esterification of crude cyanoacetic acid with a monohydric alcohol which forms an azeotrope with water and has 4 to 10 carbon atoms, reacting the resulting ester with ammonia in the presence of a basic catalyst to give cyanoacetamide, and work-up by a mechanical separating operation and a thermal treatment.

Process for preparing cyanoacetamide

A process for the preparation of cyclopropanamine by Hofmann degradation of cyclopropanecarboxamide, comprising the following steps:

Process for the preparation of cyclopropanamine

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Herne, Germany

Thomas Kalz