Genetronics, Inc.

Vgx Pharmaceuticals, Inc.

Inovio Pharmaceuticals, Inc.

Thomas Joseph Kardos

Rune Kjeken

Stephen Vincent Kemmerrer

Jay R McCoy

Kate Broderick

Dietmar P Rabussay

Stephen V Kemmerrer

Feng Lin

Jay Mccoy

Michael P Fons

Stephen Vincent Kemmerer

This invention comprises an improved electroporation electrode system comprising a single needle and a ring or donut shaped electrode wherein the difference in surface area of the electrodes provide for a substantial reduction of current density near the surface of the treated tissue and a more concentrated current density sufficient for electroporation only in tissues adjacent to the terminal portion of the single needle electrode. Thus, this invention provides for targeting specific tissue for electroporation and also should provide for lessening the sensation of electric current in the treated tissue.

Variable current density single needle electroporation system and method

Devices and methods for delivering an electropermeabilizing pulse of electric energy to a tissue surface to enable delivery into cells in the tissue therapeutic substances. The device incorporates a source capable of generating a sufficient voltage potential to deliver a spark across a gap and delivers same to the tissue surface.

Contactless electropermeabilization electrode and method

Growing community of inventors

Aliso Viejo, CA, United States of America

Thomas Joseph Kardos