Advanced Applied Physics Solutions, Inc.

Triumf

Thomas J. Ruth

Stefan K. Zeisler

Kenneth R. Buckley

Thomas J Ruth

Suzanne Lapi

Dirk W Becker

John M D'Auria

Stefan K Zeisler

Kenneth Robert Buckley

Paul Schaffer

Victoire Hanemaayer

Thomas J Morley

John Valliant

Maurice G Dodd

Cornelia Manuela Hoehr

Julius Alexander Klug

Michael S Kovacs

Salma Jivan

Kwonsoo Chun

Kenneth R Buckley

Cornelia Hoehr Manuela

Cornelia Manuela

A system for producing technetium-99m from molybdate-100. The system comprises: a target capsule apparatus for housing a Mo-100-coated target plate; a target capsule pickup apparatus for engaging, and delivering the target cell apparatus into a target station apparatus; target station apparatus for receiving and mounting therein the target capsule apparatus. The target station apparatus is engaged with a cyclotron for irradiating the Mo-100-coated target plate with protons. The irradiated target capsule apparatus is transferred to a receiving cell apparatus comprising a dissolution/purification module for receiving therein a proton-irradiated Mo-100-coated target plate. A conveyance conduit infrastructure interconnects: (i) the target capsule pickup apparatus with the target station apparatus, (ii) the target station apparatus and the receiving cell apparatus; and (iii) the receiving cell apparatus and the dissolution/purification module.

Processes, systems, and apparatus for cyclotron production of technetium-99m

A method of isolatingMo produced using a (n,&#x3b3;) reaction according to example embodiments may include vaporizing a source compound containingMo andMo. The vaporized source compound may be ionized to form ions containingMo andMo. The ions may be separated to isolate the ions containingMo. The isolated ions containingMo may be collected with a collector. Accordingly, the isolatedMo may have a relatively high specific radioactivity and, in turn, may be used to produce the diagnostic radioisotope,Tc, through radioactive decay.

Method and apparatus for isolating the radioisotope molybdenum-99

A method of isolating a radioisotope according to example embodiments may include vaporizing a source compound containing a first isotope and a second isotope of an element, wherein the second isotope may have at least one of therapeutic and diagnostic properties when used as a radiopharmaceutical. The vaporized source compound may be ionized to form charged particles of the first and second isotopes. The charged particles may be separated to isolate the particles of the second isotope. The isolated charged particles of the second isotope may be collected with an oppositely-charged collector. Accordingly, the isolated second isotope may be used to produce therapeutic and/or diagnostic radiopharmaceuticals having higher specific activity.

Method and apparatus for isolating a radioisotope

A method of isolatingRe according to example embodiments may include vaporizing a source compound containingRe andRe. The vaporized source compound may be ionized to form negatively-charged molecules containingRe andRe. The negatively-charged molecules may be separated to isolate the negatively-charged molecules containingRe. The isolated negatively-charged molecules containingRe may be collected with a positively-charged collector. Accordingly, the isolatedRe may be used to produce therapeutic and/or diagnostic radiopharmaceuticals having higher specific activity.

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A system and method for producingF-Fluoride by using a proton beam to irradiateOxygen in gaseous form. The irradiatedOxygen is contained in a chamber that includes at least one component to which the producedF-Fluoride adheres. A solvent dissolves the producedF-Fluoride off of the at least one component while it is in the chamber. The solvent is then processed to obtain theF-Fluoride.

System and method for the production of 18F-Fluoride

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Vancouver, Canada

Thomas J Ruth