Target Therapeutics, Inc.

Integrated Vascular Systems, Inc.

General Surgical Innovations, Inc.

Aquedeon Medical, Inc.

Cordis Corporation

Radiotherapeutics Corporation

Aesculap Ag

Ensure Medical, Inc.

Boston Scientific Scimed, Inc.

Scimed Life Systems, Inc.

Tyco Healthcare Group LP

Cardinal Health Switzerland 515 Gmbh

Innerdyne, Inc.

Revascular Therapeutics, Inc.

Integated Vascular Systems, Inc.

Thomas J Palermo

Richard S Ginn

Anthony J Pantages

Ronald J Jabba

Michael T Carley

William Martin Belef

Jimmy Jen

Michael J Mariant

Pin-Hsuan Lee

Kenneth A Peartree

Shigeru Tanaka

Ferolyn T Powell

Francisco Javier Sagastegui

James E Jervis

Gene L Samson

Julian N Nikolchev

Arkady Kokish

Laveille Kao Voss

Son M Gia

Robert S Behl

T Daniel Gross

U Hiram Chee

Brian Andrew Ellingwood

Kelly Justin McCrystle

Benjamin J Matthias

Colin J Nichols

Roderick A Young

Phong Pham

Gregory E Mirigian

Phil Olsen

Nicholas J Terzulli

Tellis Hartridge

Kevin Van Bladel

Lawrence R Tyler

Adam Shively

Hans J Zwart

Kevin L Hudelson

Erik T Engelson

Kim D Nguyen

Vipul Bhupendra Dave

John E Carlson

Pete Phong Pham

Edward J Snyder

Craig K Tsuji

Steven P Masterson

Robert K Deckman

Chao-Chin Chen

Chao Chin-Chen

Jeffrey Rydin

Chi J Chung

Javier Sagasteguei

Javier Saguasteguei

A vascular connector deployment tool may include a handle, an elongated mandrel extending distally from the handle, a vascular connector disposed coaxially about the mandrel, a retractable sheath assembly including an outer sheath telescopically deployed over an inner sheath and an actuator on the handle that is configured to selectively retract the outer sheath and the inner sheath relative to the mandrel. The sheath assembly is configured to constrain the vascular connector against the mandrel in an insertion profile. A distal transition between the outer sheath and the inner sheath visually indicates position of the vascular connector.

Vascular and aortic grafts with telescoping sheath and deployment methods thereof

A hybrid graft and method for implantation in a blood vessel of a patient is described. The hybrid graft may include a graft portion having proximal and distal ends and an expandable mesh secured to the distal end of the graft portion. The expandable mesh is configured to transition from an insertion to a deployed diameter. The hybrid graft may also include a tubular sleeve having a lumen configured to receive a part of the graft portion and the expandable mesh and a suture cuff positioned adjacent the expandable mesh. During deployment, the distal end of the hybrid graft is inserted through an opening in the blood vessel wall or an end of the vascular graft and expanded from the insertion to the deployed diameter to secure the hybrid graft within the blood vessel or vascular graft. The suture cuff is sutured to the blood vessel or vascular graft.

Vascular and aortic grafts and deployment tool

A vascular graft may be configured to transition from an insertion state to a deployed state. The graft comprising a proximal end having an expandable mesh, a distal end having an expandable mesh, and at least one suture cuff positioned between the proximal and distal ends, wherein each suture cuff comprises additional material relative to the proximal and distal ends that is configured to form when the vascular graft transitions from the insertion state to the deployed state.

Vascular and aortic grafts and deployment tools

A vascular graft deployment tool may include a grip, an elongated mandrel positioned distal of the grip, a vascular graft, at least part of which is disposed coaxially about the mandrel, a sheath configured to be withdrawn proximally that constrains the vascular graft against the mandrel in an insertion diameter and an actuator that is moveable relative to the grip and engages the sheath assembly. A first operation of the actuator causing withdrawal of the sheath to free at least a distal portion of the vascular graft and a repeated operation of the actuator causing further withdrawal of the sheath to free a proximal portion of the vascular graft.

A vascular graft deployment tool may include a grip, an elongated mandrel positioned distal of the grip, a vascular graft, at least part of which is disposed coaxially about the mandrel, a sheath assembly including a distal sheath portion and a proximal sheath potion, wherein the distal sheath portion and the proximal sheath portion are configured to constrain the vascular graft against the mandrel in an insertion diameter and a actuator that is moveable relative to the grip and engages the sheath assembly, wherein operation of the actuator causes at least one of the distal sheath portion and the proximal sheath portion to separate longitudinally to free at least a portion of the vascular graft. Further, a vascular graft is expandable from an insertion state to a deployed state and at least two suture cuffs are located between opposed ends of the vascular graft.

A system having an elongate assembly, an expandable assembly having a fixed end region and a movable end region, the expandable assembly selectively transitioning between an expanded state and an unexpanded state with movement of the movable end region towards the fixed end region, and an advancement aid extending distally from the expandable assembly.

Clip applier and methods of use

An exemplary surgical method includes possessing a loader that holds a curved-tip cartridge, and a surgical stapler that includes an anvil and channel at a distal end thereof; causing at least one of the loader and the channel to move toward the other; as a result of the causing, engaging the loader and the curved-tip cartridge with the channel; and causing at least one of the loader and the channel to move away from the other, such that the curved-tip cartridge remains engaged with the channel. That method further may include actuating the surgical stapler; grasping the unloader; sliding the unloader toward the channel; disengaging the curved-tip cartridge from the channel with the unloader; and withdrawing the unloader away from said channel, wherein the withdrawing causes the curved-tip cartridge to disengage from the channel.

Surgical stapler cartridge loading and unloading

A vessel closure device delivery system including a delivery device that couples to a vessel closure clip for delivering the clip onto a blood vessel and a retractable vessel locator is removeably attached to the delivery device, the distal end of the vessel locator being adapted to transition from a collapsed state suitable for insertion into a vessel and an expanded state that lodges against a wall of the vessel from inside the vessel.

A luminal drilling system includes a drilling device and a control unit. The drilling device includes an elongate member having a drive shaft with a drill tip. The control unit includes a motor connectable to the drive shaft and control circuitry which rotationally oscillates the drive shaft with the direction of rotation automatically reversing whenever the load on the motor and/or drive shaft exceeds a threshold value.

Method and system for reversibly controlled drilling of luminal occlusions

This invention relates to apparatus and methods used to seal a vascular puncture site, particularly sites of punctures that are the result of catheterization or other interventional procedures. The sealing device includes a sealing member and a tether. The sealing member occupies a space in an incision, puncture, or other wound and sealing the space that it occupies, to prevent further blood flow. The tether is attached to the sealing member, and provides the user with the ability to withdraw the sealing member if necessary. The sealing device further includes a restraining member associated with the sealing member. The restraining member provides the ability to more securely restrain the sealing member to prevent it from migrating from the deployment location within a tissue tract. The restraining member also provides an additional capability of manipulating the sealing member after deployment.

Vascular plug having composite construction

The present invention is directed to a method for sealing a puncture in a wall of a lumen of a body comprising the steps of deploying a deployment member of a sealing device through an elastic membrane adjacent the wall of the lumen and the puncture, wherein the sealing device includes a sealing element; positioning the sealing element adjacent the wall of the lumen; retracting the deployment member relative to the sealing element to stretch the membrane away from the wall of the lumen; retracting the deployment member relative to the sealing element to allow the elastic nature of the membrane to force the sealing element against the puncture; and retracting the device from the puncture.

Locator and closure device and method of use

An apparatus for delivering a closure element can include a splittable carrier tube and a splitter to split the tube. The carrier tube can have an outer surface retaining a closure element in a tubular configuration and can be split into radially-expandable flaps. A closure element can have a shape-memory body having a relaxed configuration with a planar-annular body defining a lumen with tines directed inwardly from the body. The clip can be held in a retaining configuration having a substantially asymmetrically-elongated tubular shape with a trapezoidal longitudinal cross-sectional profile and a proximal end having the tines being longitudinally directed with a first tine being more distally oriented compared to a substantially opposite second tine being more proximal, and retracting to a deploying configuration having a tubular shape with a rectangular longitudinal cross-sectional profile with the first tine being even with the second tine when being delivered.

The present invention is directed to a device which is capable of both locating a punctured blood vessel wall and sealing the puncture in the vessel and to the method of using the device as well. In one embodiment, the device includes an elongate deployment member having a sealing element releasably disposed within a distal end thereof, said deployment member being coupled to a first actuator configured to retract said deployment member relative to said sealing element, and an elongated indicator member having a proximal end and a distal end, said indicator member extending through a lumen in said deployment member such that the distal end of said indicator member extends distally of the distal end of the deployment member, and said indicator member being coupled to a second actuator configured to retract said indicator member relative to said deployment member.

An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.

Growing community of inventors

San Jose, CA, United States of America

Thomas J Palermo