The University of British Columbia

Triumf

Thomas J Morley

Stephen G Withers

Paul Schaffer

Thomas J Ruth

Stefan K Zeisler

Kenneth Robert Buckley

Victoire Hanemaayer

Cornelia Manuela Hoehr

Maurice G Dodd

Julius Alexander Klug

Michael S Kovacs

John Valliant

Lars Baumann

Cornelia Hoehr Manuela

Kenneth R Buckley

Cornelia Manuela

A system for producing technetium-99m from molybdate-100. The system comprises: a target capsule apparatus for housing a Mo-100-coated target plate; a target capsule pickup apparatus for engaging, and delivering the target cell apparatus into a target station apparatus; target station apparatus for receiving and mounting therein the target capsule apparatus. The target station apparatus is engaged with a cyclotron for irradiating the Mo-100-coated target plate with protons. The irradiated target capsule apparatus is transferred to a receiving cell apparatus comprising a dissolution/purification module for receiving therein a proton-irradiated Mo-100-coated target plate. A conveyance conduit infrastructure interconnects: (i) the target capsule pickup apparatus with the target station apparatus, (ii) the target station apparatus and the receiving cell apparatus; and (iii) the receiving cell apparatus and the dissolution/purification module.

Processes, systems, and apparatus for cyclotron production of technetium-99m

This invention provides compound having a structure of Formulas: Furthermore, methods and uses of such compounds for covalently bonding to a sugar acceptor, to form modified protein therapeutics having reduced enzymatic hydrolysis, improved biological stability or an improved pharmacokinetic property. 

Hydrolysis resistant sialic acid derivatives and methods for their use

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New Haven, CT, United States of America

Thomas J Morley