Novartis Ag

Biocure Limited

Ivoclar Vivadent Ag

Ciba Vision Corporation

Xennia Technology Limited

Lu, Zhihua

Asfaw, Bruktawit T.

Shums, Sameer

Zhai, Xiaowen

Hu, Xianbo

Rene, Claude-raymond

Jackson, John C.

Hirt, Thomas

Thomas Hirt

Dieter Lohmann

Troy Vernon Holland

Jacalyn Marie Schremmer

Norbert Moszner

Richard Carlton Baron

Volker Rheinberger

Qin Liu

Peter Burtscher

Ulrich Salz

Urs Karl Fischer

Ulrich Sigmar Schubert

Hassan Chaouk

James Edward Fox

Aaldert Rens Molenberg

Jens Hopken

Wilson Leonard Terry, Jr

Christoph Weder

Bruktawit T Asfaw

Kai Rist

Martin Hager

Jacalyn Mary Schremmer

Wolfgang Meier

Vimala Mary Francis

Claude-Raymond René

Gina Fiore

Bobby Happ

Benedict Sandmann

Corinne Nardin

Zhihua Lu

Wolfgang Peter Meier

Kay K Yeong

Xianbo Hu

Sameer Shums

Xiaowen Zhai

John C Jackson

Christian Heinzmann

The invention relates to a dental restorative material on the basis of at least one compound of Formula IA-[X-Q-(Y-CG)]&#x2003;&#x2003; Formula I,wherein CG represents in each case independently an azide group Nor an alkyne group selected from the group consisting of &#x2014;CRR&#x2014;C&#x2261;CH, with the proviso that the dental restorative material comprises at least one compound of Formula I comprising an azide group and at least one compound of Formula I comprising an alkyne group. The invention also relates to the use of the dental restorative materials according to the invention for preparing dental composites, preferably composite blanks, which are suitable in particular for mechanical processing by means of computer-aided processing techniques such as milling and grinding processes, and which are suitable above all for preparing dental restoration materials such as inlays, onlays, crowns, bridges or veneering materials.

Dental restorative materials based on polymerizable azides and alkynes

The invention relates to a dental restorative material which comprises a thermolabile compound of Formula I:[(Z)-Q-X)]-T-[Y-Q-(Z)]&#x2003;&#x2003;Formula I,in which T represents a thermolabile unit which contains at least one thermolabile group based on non-covalent interactions, Zand Zin each case independently represent a polymerizable group selected from vinyl groups, CH&#x2550;CR&#x2014;CO&#x2014;O&#x2014; and CH&#x2550;CR&#x2014;CO&#x2014;NR&#x2014; or an adhesive group selected from &#x2014;Si(OR), &#x2014;COOH, &#x2014;O&#x2014;PO(OH), &#x2014;PO(OH), &#x2014;SOOH and &#x2014;SH, Qin each case independently is missing or represents an (m+1)-valent linear or branched aliphatic C-Cradical which can be interrupted by &#x2014;O&#x2014;, &#x2014;S&#x2014;, &#x2014;CO&#x2014;O&#x2014;, &#x2014;O&#x2014;CO&#x2014;, &#x2014;CO&#x2014;NR&#x2014;, &#x2014;NR&#x2014;CO&#x2014;, &#x2014;O&#x2014;CO&#x2014;NR&#x2014;, &#x2014;NR&#x2014;CO&#x2014;O&#x2014; or &#x2014;NR&#x2014;CO&#x2014;NR&#x2014;, Qin each case independently is missing or represents an (n+1)-valent linear or branched aliphatic C-Cradical which can be interrupted by &#x2014;O&#x2014;, &#x2014;S&#x2014;, &#x2014;CO&#x2014;O&#x2014;, &#x2014;O&#x2014;CO&#x2014;, &#x2014;CO&#x2014;NR&#x2014;, &#x2014;NR&#x2014;CO&#x2014;, &#x2014;O&#x2014;CO&#x2014;NR&#x2014;, &#x2014;NR&#x2014;CO&#x2014;O&#x2014; or &#x2014;NR&#x2014;CO&#x2014;NR&#x2014;, X and Y in each case independently are missing or represent &#x2014;O&#x2014;, &#x2014;S&#x2014;, CO&#x2014;O&#x2014;, &#x2014;O&#x2014;CO&#x2014;, &#x2014;CO&#x2014;NR&#x2014; or &#x2014;NR&#x2014;CO&#x2014;, R, R, Rand Rin each case independently represent H or a C-Calkyl radical, k and l in each case independently are 0, 1, 2 or 3 and m and n in each case independently are 1, 2 or 3.

Dental materials based on compounds having debonding-on-demand properties

A composition comprising a macromer that can be in situ polymerized into a hydrogel wound dressing directly on a wound and one or more antimicrobial agents intended to achieve bacteriostasis and/or be bacteriocidal. The antimicrobial agent is released upon application and trapped in the hydrogel upon its formation and also released over a period of time into the wound.

In-situ forming hydrogel wound dressings containing antimicrobial agents

A method and a printing device () for decorating glass or ceramic items, wherein a pigment layer () is sandwiched between two glass frit layers (), wherein at least the pigment formulation layer () and the upper glass frit formulation layer () are, or can be, imprinted by an inkjet printing process.

Method, printing device, and formulations for decorating glass or ceramic items

The invention relates to novel crosslinkable copolymers of formula wherein the variables are as defined in the claims. The copolymers of the invention are especially useful for the manufacture of biomedical moldings, for example ophthalmic moldings such as in particular contact lenses.

Amphiphilic block copolymers

Organic compounds

The invention relates to novel crosslinkable copolymers of formula wherein the variables are as defined in the claims. The copolymers of the invention are especially useful for the manufacture of biomedical molding, for example ophthalmic moldings such as in particular contact lenses.

Vesicles made from amphiphilic copolymers are disclosed. The amphiphilic copolymers can be ABA copolymers, where one of A and B is hydrophilic and the other is hydrophobic. AB copolymers can also be used. The copolymers may be crosslinked to form nanocapsules. Crosslinking can be accomplished using a variety of methods, including end to end polymerization of copolymers having terminal unsaturated groups. Molecules, such as membrane proteins, can be incorporated into the wall of the vesicles or nanocapsules.

Amphiphilic polymeric vesicles

Biodegradable biocompatible hydrogels based on poly(vinyl alcohol) and methods for their preparation. The methods for preparation of the hydrogels involve the use of prepolymers. The prepolymers have a PVA backbone and pendant chains that include a polymerizable group. In one embodiment, the pendant chains also include a biodegradable region. In another embodiment, biodegradable regions are incorporated into the hydrogel during its formation.

Degradable poly(vinyl alcohol) hydrogels

Organic polymers

The present invention relates to a process for the manufacture of a molding, which comprises the following steps:

Process for the manufacture of an ophthalmic molding

The subject matter of the present invention is an amphiphilic, segmented copolymer of controlled morphology comprising at least one segment having high oxygen permeability, at least one segment having high ion and water permeability, the segments being linked together through a non-hydrolizable bond, and at least one polymerizable unsaturated group; a process for the preparation of the copolymer; to polymeric products obtainable by further polymerizing and optionally cross-linking the amphiphilic segmented copolymer, and to mouldings, especially contact lenses and other ophthalmic devices comprising a polymeric product of the invention. In a specifically preferred embodiment, the present invention relates to a contact lens comprising a polymeric product of the invention which is suited for extended periods of wear.

Amphiphilic, segmented copolymer of controlled morphology and ophthalmic

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Rebstein, Switzerland

Thomas Hirt