Sanofi-a Ventis Deutschland Gmbh

Intima Bioscience, Inc.

Thomas Henley

Douglas Ivan Jennings

David Murray Cross

Ryan Anthony McGinley

Mavis Agbandje-McKenna

Modassir Choudhry

Tilmann Buerckstuemmer

Lydia Viney

Ryan Anthony Mcginley

Genetically modified compositions, such as adeno-associated viral vectors and primary cells, for treating various conditions and diseases. Disclosed are also modified adeno-associated viruses for the treatment of cancer. Also disclosed are the methods of making and using the genetically modified compositions in treating various diseases, conditions, and cancer.

Adeno-associated viral vectors for gene therapy

Described is an autoinjector comprising a case, a drive carriage disposed in the case, and a plunger coupled to the drive carriage. The plunger is adapted to releasably engage a needle retraction mechanism in a syringe. Translation of the drive carriage in a distal direction relative to the case causes the plunger to engage the needle retraction mechanism and translation of the drive carriage in a proximal direction relative to the casing case the plunger to needle retraction mechanism the stopper.

Auto-injector

Described is an autoinjector comprising a front case having a first rib and a second rib, and a rear case telescopically coupled to the front case and having latch arms adapted to engage the first rib and the second rib. When the front case is in a first position relative to rear case, the latch arms are engaged to the first rib. When the latch arms disengage the first rib, the front case translates to a second position relative to the rear case, an axial distance between the front case and the rear case increases relative to the first position, the latch arms engage the second rib.

Autoinjector

Growing community of inventors

Cambridgeshire, United Kingdom

Thomas Henley