W. L. Gore & Associates, Inc.

Thomas G Triebes

Deenu G Kanjickal

James J Nickerson

Cody L Hartman

Bret J Kilgrow

Joseph B Koenig

Jane K Bohn

Carey V Campbell

Benjamin M Trapp

Mei Li

Robert L Cleek

Bruce M Steinhaus

Theresa A Holland

Thane L Kranzler

Edward H Cully

Michael J Vonesh

Paul D Drumheller

Peter Heicksen

James F Davidson

Daniel L Crandall

Gregory LoStracco

Gregory Lostracco

The present disclosure describes implantable medical devices comprising covers, such as a balloon cover. Such devices can comprise a first layer of a porous polymeric material, such as ePTFE, surrounded by layers of a porous polymeric material having an imbibed elastomer, such as polyurethane. The cover can be used to assist in deployment of an expandable implant, such as a stent-graft, within the body of the patient.

Inflatable balloon and cover

An improved medical device reduces the loss of longitudinal length during expansion of a stent-graft from a compressed state to an expanded state. For example, the stent-graft is placed over a cover that provides resistance to expansion of the balloon during inflation, which reduces longitudinal compressing forces exerted on the stent-graft.

Balloon expandable endoprosthesis

Inflatable balloon and cove

Methods of manufacturing a cover for an inflatable balloon

The invention is directed to delivery medical devices that enable consistent 'on-demand' delivery of therapeutic agents to a vessel. The medical device of the current invention comprises retractable sheath comprising neckable elements. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and a retractable outer sheath with a selectively permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during retraction of the outer sheath, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.

Retractable sheath devices, systems, and methods

The invention is directed to eluting medical devices that enable consistent 'on-demand' delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.

Eluting medical devices

Growing community of inventors

Flagstaff, AZ, United States of America

Thomas G Triebes