Airware, Inc.

Other

Liquid Sensing, Inc.

Clearleap, Inc.

Stratos Medtech Holdings Pty Ltd

Thomas G Campbell

Jacob Y Wong

James C Tanner

John Vecchio

Drake Henderson

Ross James Mangelsdorf

Michael Phillip Monsour

A closed, gravity-fed burette for intravenous (IV) fluid delivery and flush system supporting multiple input combinations for simplicity and standardization. Able to handle both hazardous and non-hazardous drugs, this system may incorporate plastic and elastomeric materials that are resistant to the effects of antineoplastic materials in conjunction with a hazardous air filter module while still integration compatible with electronic peristaltic pumps for finer control of flow rate and when the IV infusion recipient's physical position is not compatible with a gravity-fed flow. The buoyant-activated shuttle valve enables the AutoStart function providing steady flush of the IV line to the patient for optimized vein patency from the Primary IV fluid feed. This Primary line works in conjunction with a Secondary IV fluid feed and a needleless connector Drug Port for multiple feed and flush conditions directed by way of a monoblock design supporting combinations of rotary, toggle, and check valves.

Gravity-fed burette system

A controller and a distal sensor module are used to emit optical emissions to a liquid sample being tested in a human body and detect desired optical data which the controller uses to electronically calculate a concentration measurement of a targeted analyte (e.g., glucose). The distal sensor module is held in place by a retention mechanism while a clamping system applies clamping pressure to the liquid sample during a test period to maintain a specified sample height of the liquid sample. An optical cable is intermediate the controller and the distal sensor module and is pluggably connected to the controller. Continuous monitoring of the analyte is possible without disconnecting the controller from the optical cable or the distal sensor module from the patient while clamping pressure on the test sample is reduced outside of the test period.

Pluggable distal measurement interface

An absorption spectroscopy process uses a single radiation beam with two or more pulsed beams (including at least a signal beam and a reference beam) that are passed into a liquid sample to a variable effective depth and then reflected out of the liquid sample where it is detected and processed to obtain a value over a preselected time. As values are determined for multiple effective depths, a sampling dataset is obtained which is used to calculate a concentration level of a targeted particle in the liquid sample by use of calibration dataset obtained from use of known samples.

Reflective depth interrogation for analyte measurement in liquids

Increased precision for liquid absorption spectroscopy, especially for in vivo samples of human analytes, is obtained by varying the signal or signal and interference central wavelengths when the temperature of the sample site varies beyond a selected threshold used for determining standardized signal or signal and interference central wavelengths. The amount of variance for a central wavelength of the signal beam which includes 1,150 nm is approximately 2 nm or less.

Temperature adjusted modulation of a signal center wavelength in liquid absorption spectroscopy

A process quantifies a concentration of a targeted molecule in a liquid sample by pulsing signal and reference beams from their own sources, then spatially combining the pulsed beams into a single radiation beam which passes into the liquid sample and then detecting pulsed output beams after the single radiation beam passes out of the liquid sample. The pulsed outputs of the signal and reference beams are processed to obtain a value over a preselected period of time and, if an interference beam is used, it is processed with the reference beam to obtain a calibration curve adjustment representative of optical interference represented by at least one interfering molecule concentration which is used to calculate the concentration level of the targeted particle in the liquid sample. Two detectors, which may have an optical co-axial configuration, can be used for detection of pulsed beams.

Minimization of noise in optical data capture for liquids

The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Enhanced optical data capture using NDIR for liquids

A process and sensor system useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix wherein the sample volume is configured so that a sampling error caused by changes of the targeted molecule passing in and out of the sample volume is approximately the same or less than a measurement error caused by an accuracy limit of electronic components and optical elements used in the sensor system.

For determining concentration of targeted molecules Min a liquid sample admixed with interfering molecules Mwhich overlap their absorption band, a special NDIR sampling and calibration technique is employed. Besides the signal source, a reference and one or more interference sources are added. The selection of the wavelength for the interference sources enables its measured transmittance value to be used for deciding the validity of the calibration curve for molecules Min the liquid sample. This value can further be used to adjust the calibration curve via a parameter linking the transmittances measured at the signal and interference wavelength channels in order to assure its validity.

NDIR glucose detection in liquids

A glucose sensor measures glucose molecules in vivo through use of NDIR in which scattering noise is reduced and Absorption Interference Noise (AIN) is suppressed with a reflection technique. Electronics are used to provide an output of glucose concentration glucose in a liquid sampling matrix after it has been determined that a calibration curve is valid after signal processing is used to obtain average ratio values for reflected signal/reference channels and interference/reference channel obtained after a pulsed beam from signal, interference and reference sources is directed at an inclined angle to a normal of a spot of the liquid sampling matrix. The signal, interference and reference sources are each pulsed at a preselected frequency of at least N Hz which is sufficiently fast so that a given molecule of glucose or interfering molecule will not pass in and out of the liquid sampling matrix within the preselected frequency.

For determining concentration of a targeted molecule M in a liquid sample admixed with interfering molecules Mwhich overlap its absorption band, a NDIR reflection sampling technique is used. Besides the signal source, a reference and an interference source are added. M is calculated by electronics which use R(t) from a pulsed signal and reference channel output and a calibration curve which is validated by use of R(t) from a pulsed interference and reference channel output. Signal, interference and reference sources are pulsed at a frequency which is sufficiently fast so that a given molecule of M or Mwill not pass in and out of the liquid sampling matrix within the pulsing frequency.

NDIR reflection sampling in liquids

The window-hanging vehicle-locating device is configured for use with a vehicle. The window-hanging vehicle-locating device is removably attached to a window of the vehicle. The window-hanging vehicle-locating device is an optical signaling device that is attached to the vehicle for the purpose of visually locating the position of the vehicle. The window-hanging vehicle-locating device is remotely controlled in a manner that allows for the identification of a specific vehicle within parking lot. The window-hanging vehicle-locating device comprises a clip, a telescopic pole, a flag, a lamp, a remote interface circuit, and a user control. The flag and the lamp attach to the telescopic pole. The telescopic pole and the remote interface circuit attach to the clip. The clip attaches the window-hanging vehicle-locating device to the superior edge of the window. The user control remotely controls the operation of the window-hanging vehicle-locating device.

Window-hanging vehicle-locating device

NDIR is used to determine a concentration of a chosen molecule M in a liquid sample which contains one or more interfering molecules Mwhich absorb radiation at the signal wavelength used in the NDIR process by addition of an interference source. M is calculated by electronics which use R(t) from a pulsed signal and reference channel output and a calibration curve which is validated by use of R(t) from a pulsed interference and reference channel output. Signal, interference and reference sources are pulsed at a frequency which is sufficiently fast so that a given molecule of M or Mwill not pass in and out of the liquid sampling matrix within the pulsing frequency.

NDIR interference control in liquids

A concentration of glucose in a blood sample is determined through use of a signal channel output/reference channel ratio obtained by use of an NDIR absorption technique in which scattering noise attributable to the liquid phase is reduced by alternately and successively pulsing infrared radiation from signal and reference sources which are multiplexed and collimated into a pulsed beam directed through the sample space containing the liquid phase and the pulse frequency is sufficiently fast so that a given molecule of glucose will not pass in and out of the sample space within the pulse frequency.

Reduction of scattering noise when using NDIR with a liquid sample

A concentration of a chosen molecule in a liquid phase in a sample space is determined through use of a signal channel output/reference channel ratio obtained by use of an NDIR absorption technique in which scattering noise attributable to the liquid phase is reduced by alternately and successively pulsing infrared radiation from signal and reference sources which are multiplexed and collimated into a pulsed beam directed through the sample space containing the liquid phase and the pulse frequency is sufficiently fast so that a given molecule of the chosen molecule will not pass in and out of the sample space within the pulse frequency.

Growing community of inventors

Newbury Park, CA, United States of America

Thomas G Campbell