Dexcom, Inc.

Unl Holdings LLC

Unitract Syringe Pty Ltd

Illumina Corporation

Thomas F McGee

Mark C Brister

Sean T Saint

Paul V Neale

Daniel Steven Kline

Daniel Shawn Codd

David Michael Petersen

James Patrick Thrower

James R Petisce

Kevin Lee Bokelman

George M Wohlhieter

David R Jansen

Arthur G Marlin

Stefanie A Hurowitz

Ellen Ni Chathail

Apurv Ullas Kamath

John A Guerre

Kun-Chi Wu

Anthony John De Ruyter

Patrick Kehl

An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor. The novel incorporation of the drive control mechanisms into the automatic injectors of the present invention enables a single motor and transmission assembly to drive the function of multiple components, which may include the steps of: preparation and alignment of a cartridge for injection, removal of a safety cap or needle shield, needle injection, drug dose delivery, and syringe and/or needle retraction. Methods of manufacture and methods of use are also disclosed.

Drive control mechanisms and automatic injectors for injectable cartridges

A flow cell and cartridge assembly may be loaded into a processing system, such as for genetic sequencing. The system locates the assembly and is then actuated to move the assembly to a desired reference position in both X- and Y-directions. Further actuation causes clamps to contact the flow cell, the cartridge, or both to exert a hold-down force during processing. Further hold-down forces may be provided by a vacuum chuck. Fluid connections are also made by manifolds that contact the flow cell. The hold-down forces counteract the forces needed for sealing the manifolds to the flow cell.

Flow cell assembly securement system and method

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Transcutaneous analyte sensor

Automatic injector

Methods and systems for inserting a transcutaneous analyte sensor

Growing community of inventors

San Diego, CA, United States of America

Thomas F McGee