The Upjohn Co.

Thomas F Brodasky

Lester A Dolak

Alice L Laborde

Oldrich K Sebek

Thomas M Castle

David W Stroman

Fritz Reusser

Alexander D Argoudelis

Novel antibiotic U-68,204 is produced in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces thiolactonus, NRRL 15439. This antibiotic is active against various Gram-positive bacteria. Thus, antibiotic U-68,204 can be used in various environments to eradicate or control such bacteria.

Antibiotic producing Streptomyces thiolactonus

Novel antibiotic U-56,407 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces hagronensis strain 360, NRRL 15064. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus, Streptococcus pyogenes and Streptococcus pneumoniae. Thus, antibiotic U-56,407 can be used in various environments to eradicate or control such bacteria.

Antibiotic compound and process for recovery thereof from a fermentation

Composition of matter and process

Antibiotic acanthomycin (U-53,827) produced by the controlled fermentation of the microorganism Streptomyces espinosus subsp. acanthus, NRRL 11081. This antibiotic and its base addition salts are active against Gram-positive bacteria. Accordingly, they can be used in various environments to eradicate or control such bacteria.

Antibiotic acanthomycin and process for preparing

A sample introduction device for introducing a vaporized sample to the ion source of a mass spectrometer of a combined gas chromatography-mass spectrographic (GC/MS) apparatus. The sample introduction device replaces the jet separator of the GC/MS apparatus. The sample introduction device includes a sample holding tube which is releasably attachable to the isolation valve between the gas chromatography column and the mass spectrometer of the GC/MS apparatus. The sample introduction device includes means for connecting the sample holding tube to a vacuum source by means of a valve so that the sample holding tube can be evacuated prior to connecting the sample holding tube through the isolation valve to the ion source of the mass spectrometer.

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Kalamazoo, MI, United States of America

Thomas F Brodasky